Results 221 to 230 of about 72,565 (297)

Insulin and IGF signaling in the brain: multilevel regulation of synaptic and network homeostasis. [PDF]

Front Endocrinol (Lausanne)
Li L, He H, Wang Y.
europepmc   +1 more source

The Recycling Endosomal (Na+, K+)/H+ Exchanger NHE6/SLC9A6 Facilitates Signal Transduction by Shuttling Cyclin‐Dependent Kinase 5 to the Plasma Membrane

Acta Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aim The alkali cation/proton exchanger NHE6/SLC9A6 regulates luminal pH homeostasis and trafficking of recycling endosomes in most tissues, especially neurons. Loss‐of‐function mutations in NHE6 cause Christianson Syndrome, an X‐linked neurodevelopmental and neurodegenerative disorder; however, the underlying molecular and cellular mechanisms ...
Rebecca Flessner, Alina Ilie, Léo Han, Annie Boucher, Rebecca Anne McKinney, Reza Sharif‐Naeini, John Orlowski   +6 more
wiley   +1 more source

Neurogranin Promotes Neuronal Maturation and Network Activity Through Ca²⁺/Calmodulin Signaling. [PDF]

Int J Mol Sci
Martínez-Blanco E, de Andrés R, López-Merino E, Esteban JA, Díez-Guerra FJ.   +4 more
europepmc   +1 more source

Dissociating role of Bassoon in glutamatergic and dopaminergic neurons in alcohol‐related behaviour and affective state in mice

British Journal of Pharmacology, Volume 183, Issue 11, Page 3111-3128, June 2026.
Abstract Background and Purpose Alcohol abuse and affective disorders are severe comorbid psychiatric diseases characterized by impaired brain synaptic transmission. The role of presynaptic scaffolding proteins coordinating presynaptic plasticity and neurotransmitter release, such as Bassoon (Bsn), in the pathogenesis of these disorders remains elusive.
Liubov S. Kalinichenko, Mona Krenbauer, Janosh Isert, Marlon Kamlah, Thorben Tanzer, Hannes Rödel, Tobias Müller, Anil Annamneedi, Enes Yağız Akdaş, Volker Eulenburg, Bernd Lenz, Eckart D. Gundelfinger, Johannes Kornhuber, Anna Fejtova, Christian P. Müller   +14 more
wiley   +1 more source

Beyond sodium channel blockade: Flavonoid as alternative local anesthetic candidates of lidocaine. [PDF]

Mol Pain
Takeda M, Utugi S, Toyota R, Sashide Y.
europepmc   +1 more source

Detection of Diagnostic Antibodies in Immune‐Mediated Diseases: A Focus on Antigens and Technologies

ChemBioChem, Volume 27, Issue 9, 14 May 2026.
This review explores autoantibody detection in immune‐mediated diseases, highlighting autoantigens including post‐translational modifications. We compared enzyme‐linked immunosorbent assay and indirect immunofluorescence with automated chemiluminescence platforms.
Silvia Bracci, Feliciana Real‐Fernandez, Federico Pratesi, Francesca Nuti, Paolo Rovero, Anna Maria Papini   +5 more
wiley   +1 more source

Layer 6 is a hub for cholinergic modulation in the mouse auditory cortex. [PDF]

Cereb Cortex
Vattino LG, Clayton KK, Hackett TA, Polley DB, Takesian AE.   +4 more
europepmc   +1 more source

Two‐Dimensional Reconfigurable Photodiode for In‐Sensor Color Filtering and Spectral Logic

Advanced Materials, Volume 38, Issue 26, 8 May 2026.
By harnessing the photodoping of different aggregates, the device exhibits wavelength‐dependent volatile‐to‐nonvolatile photoresponses that can be reconfigured via bias modulation. This enables in‐sensor color filtering and spectral‐encrypted information processing, eliminating reliance on external optical filters or post‐processing algorithms ...
Xiaokun Guo, Yaoqiang Zhou, Yufeng Zhang, Xinyi Zhao, Yue Pang, Lei Tong, Zhipei Sun, Jianbin Xu   +7 more
wiley   +1 more source

Emergence of multifrequency activity in a laminar neural mass model. [PDF]

PLoS Comput Biol
de Palma Aristides R, Clusella P, Sanchez-Todo R, Ruffini G, Garcia-Ojalvo J.   +4 more
europepmc   +1 more source

The Role of Ionic Liquids at the Biological Interfaces in Bioelectronics

Advanced Science, Volume 13, Issue 26, 8 May 2026.
Ionic liquids (ILs) are highlighted as key artificial ionic materials that bridge biological ion‐based signaling and electronic devices. By understanding their composition, structure, function relationships, and mechanisms, ILs can advance from high performance electrolyte to core materials enabling integrated, multifunctional bioelectronics for ...
Yeong‐sinn Ye, Young Jin Jo, Ji Yeon Oh, Ju Yeon Jeong, Lili Guo, Tae‐il Kim   +5 more
wiley   +1 more source