Results 21 to 30 of about 47,587 (242)
eLife, 2023 Axons are equipped with the digital signaling capacity by which they generate and faithfully propagate action potentials (APs), and also with the analogue signaling capacity by which subthreshold activity in dendrites and soma is transmitted down the ...
Federico Trigo, Shin-ya Kawaguchi
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γ-Hydroxybutyrate inhibits excitatory postsynaptic potentials in rat hippocampal slices
European Journal of Pharmacology, 1999 Gamma-Hydroxybutyrate (GHB) has been shown to mimic different central actions of ethanol, to suppress alcohol withdrawal syndrome, and to reduce alcohol consumption both in rats and in humans. The aim of the present study was to determine if GHB shared with alcohol the ability to inhibit glutamate action at both NMDA and AMPA/kainate receptors.
BERTON, FULVIA +6 more
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Active summation of excitatory postsynaptic potentials in hippocampal CA3 pyramidal neurons [PDF]
Proceedings of the National Academy of Sciences, 1998 The manner in which the thousands of synaptic inputs received by a pyramidal neuron are summed is critical both to our understanding of the computations that may be performed by single neurons and of the codes used by neurons to transmit information. Recent work on pyramidal cell dendrites has shown that subthreshold synaptic inputs are modulated by ...
N N, Urban, G, Barrionuevo
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SAPAP3 regulates epileptic seizures involving GluN2A in post-synaptic densities
Cell Death and Disease, 2022 Aberrantly synchronized neuronal discharges in the brain lead to epilepsy, a devastating neurological disease whose pathogenesis and mechanism are unclear.
Yanke Zhang +12 more
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Complex events initiated by individual spikes in the human cerebral cortex.
PLoS Biology, 2008 Synaptic interactions between neurons of the human cerebral cortex were not directly studied to date. We recorded the first dataset, to our knowledge, on the synaptic effect of identified human pyramidal cells on various types of postsynaptic neurons and
Gábor Molnár +8 more
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Effect of Alpha 1-Adrnoceptor Antagonists on Postsynaptic Sensitivity in Substantia Gelatinosa Neurons From Lumbosacral Spinal Cord in Rats Using Slice Patch-Clamp Technique for mEPSC [PDF]
International Neurourology Journal, 2020 Purpose Alpha1-adrenoceptors participate in improving storage symptoms of male lower urinary tract symptoms (LUTS). However, the mechanism of action of these compounds remains unclear.
Daisuke Uta +2 more
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PLoS ONE, 2011 Generative models of neuroimaging and electrophysiological data present new opportunities for accessing hidden or latent brain states. Dynamic causal modeling (DCM) uses Bayesian model inversion and selection to infer the synaptic mechanisms underlying ...
Rosalyn J Moran +8 more
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Frontiers in Neuroscience, 2020 Signaling from the synapse to nucleus is mediated by the integration and propagation of both membrane potential changes (postsynaptic potentials) and intracellular second messenger cascades.
Jian Fu +3 more
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Brain injury impairs working memory and prefrontal circuit function
Frontiers in Neurology, 2015 More than 2.5 million Americans suffer a traumatic brain injury (TBI) each year. Even mild to moderate traumatic brain injury causes long-lasting neurological effects.
Colin James Smith +5 more
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Compressed Sensing of Excitatory Postsynaptic Potential Bio-Signals
Computer Science & Information Technology ( CS & IT ), 2016 To reduce the size of the biosignal data is important because a huge amount of data is made by various experiments. In the paper, we efficiently compress the excitatory postsynaptic potentials (EPSPs) which is one of the biosignal types. To the best of authors' knowledge, EPSPs compression has not been studied yet.
Hyejin An, Hyun-Chool Shin
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