Results 21 to 30 of about 47,451 (277)

Cholinergic and Noradrenergic Modulation of Corticothalamic Synaptic Input From Layer 6 to the Posteromedial Thalamic Nucleus in the Rat

open access: yesFrontiers in Neural Circuits, 2021
Cholinergic and noradrenergic neuromodulation of the synaptic transmission from cortical layer 6 of the primary somatosensory cortex to neurons in the posteromedial thalamic nucleus (PoM) was studied using an in vitro slice preparation from young rats ...
Syune Nersisyan   +6 more
doaj   +1 more source

Anterograde Activin signaling regulates postsynaptic membrane potential and GluRIIA/B abundance at the Drosophila neuromuscular junction. [PDF]

open access: yesPLoS ONE, 2014
Members of the TGF-β superfamily play numerous roles in nervous system development and function. In Drosophila, retrograde BMP signaling at the neuromuscular junction (NMJ) is required presynaptically for proper synapse growth and neurotransmitter ...
Myung-Jun Kim, Michael B O'Connor
doaj   +1 more source

ANALYSIS OF THE SLOW EXCITATORY POSTSYNAPTIC POTENTIAL IN BULLFROG SYMPATHETIC GANGLION CELLS

open access: bronzeThe Japanese Journal of Physiology, 1976
The ionic mechanism of the slow excitatory postsynaptic potential (slow EPSP), i.e. the muscarinic action of acetylcholine (ACh), was studied either by stimulating preganglionic nerves or by applying ACh in curarized sympathetic ganglion cells of bullfrogs.
Kenji Kuba, K. Koketsu
openalex   +4 more sources

The Mechanistic Basis for Successful Spinal Cord Stimulation to Generate Steady Motor Outputs

open access: yesFrontiers in Cellular Neuroscience, 2019
Electrical stimulation of the spinal cord is a promising rehabilitation intervention to restore/augment motor function after spinal cord injury (SCI).
Amr A. Mahrous   +4 more
doaj   +1 more source

It is time to combine the two main traditions in the research on the neural correlates of consciousness: C=LxD

open access: yesFrontiers in Psychology, 2014
Research on neural correlates of consciousness has been conducted and carried out mostly from within two relatively autonomous paradigmatic traditions – studying the specific contents of conscious experience and their brain-process correlates and ...
Talis eBachmann, Anthony G Hudetz
doaj   +1 more source

Patch-clamp analysis of nicotinic synapses whose strength straddles the firing threshold of rat sympathetic neurons

open access: yesFrontiers in Neuroscience, 2022
Neurons in paravertebral sympathetic ganglia are innervated by converging nicotinic synapses of varying strength. Based upon intracellular recordings of excitatory postsynaptic potentials (EPSPs) with sharp microelectrodes these synapses were classified ...
Paul H. M. Kullmann, John P. Horn
doaj   +1 more source

Analogue signaling of somatodendritic synaptic activity to axon enhances GABA release in young cerebellar molecular layer interneurons

open access: yeseLife, 2023
Axons are equipped with the digital signaling capacity by which they generate and faithfully propagate action potentials (APs), and also with the analogue signaling capacity by which subthreshold activity in dendrites and soma is transmitted down the ...
Federico Trigo, Shin-ya Kawaguchi
doaj   +1 more source

SAPAP3 regulates epileptic seizures involving GluN2A in post-synaptic densities

open access: yesCell Death and Disease, 2022
Aberrantly synchronized neuronal discharges in the brain lead to epilepsy, a devastating neurological disease whose pathogenesis and mechanism are unclear.
Yanke Zhang   +12 more
doaj   +1 more source

Complex events initiated by individual spikes in the human cerebral cortex.

open access: yesPLoS Biology, 2008
Synaptic interactions between neurons of the human cerebral cortex were not directly studied to date. We recorded the first dataset, to our knowledge, on the synaptic effect of identified human pyramidal cells on various types of postsynaptic neurons and
Gábor Molnár   +8 more
doaj   +1 more source

Dynamic causal models and physiological inference: a validation study using isoflurane anaesthesia in rodents.

open access: yesPLoS ONE, 2011
Generative models of neuroimaging and electrophysiological data present new opportunities for accessing hidden or latent brain states. Dynamic causal modeling (DCM) uses Bayesian model inversion and selection to infer the synaptic mechanisms underlying ...
Rosalyn J Moran   +8 more
doaj   +1 more source

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