Results 81 to 90 of about 373,469 (269)
Pathway-, layer- and cell-type-specific thalamic input to mouse barrel cortex
eLife, 2019 Mouse primary somatosensory barrel cortex (wS1) processes whisker sensory information, receiving input from two distinct thalamic nuclei. The first-order ventral posterior medial (VPM) somatosensory thalamic nucleus most densely innervates layer 4 (L4 ...
B Semihcan Sermet +7 more
doaj +1 more source
Epilepsia Open, 2020 Objective Ion channels belonging to subfamily A of voltage‐gated potassium channels (Kv1) are highly expressed on axons, where they play a key role in determining resting membrane potential, in shaping action potentials, and in modulating action ...
Jiaxin Du, Viktor Vegh, David C. Reutens
doaj +1 more source
Gain-of-function mutations in the UNC-2/CaV2α channel lead to excitation-dominant synaptic transmission in C. elegans [PDF]
, 2019 Mutations in pre-synaptic voltage gated calcium channels can lead to familial hemiplegic migraine type 1 (FHM1). While mammalian studies indicate that the migraine brain is hyperexcitable due to enhanced excitation or reduced inhibition, the molecular ...
Alkema, Mark J. +9 more
core +1 more source
Scientific Reports, 2017 We present a novel, all-electric approach to record and to precisely control the activity of tens of individual presynaptic neurons. The method allows for parallel mapping of the efficacy of multiple synapses and of the resulting dynamics of postsynaptic
David Jäckel +7 more
doaj +1 more source
Tuning a binary ferromagnet into a multi-state synapse with spin-orbit torque induced plasticity [PDF]
Advanced Functional Materials, 29 (25), 1808104 (2019), 2018 Inspired by ion-dominated synaptic plasticity in human brain, artificial synapses for neuromorphic computing adopt charge-related quantities as their weights. Despite the existing charge derived synaptic emulations, schemes of controlling electron spins in ferromagnetic devices have also attracted considerable interest due to their advantages of low ...
arxiv +1 more source
Ciberial Muscle 9 (CM9) Electrophysiological Recordings in Adult Drosophila melanogaster
Bio-Protocol, 2017 The complexity surrounding presynaptic recordings in mammals is a significant barrier to the study of presynaptic mechanisms during neurotransmission in the mammalian central nervous system (CNS). Here we describe an adult fly neuromuscular junction (NMJ)
Benjamin Eaton, Rebekah Mahoney
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Synaptic Delays for Temporal Feature Detection in Dynamic Neuromorphic Processors [PDF]
Frontiers in Neuroscience; Neuromorphic Engineering (2020), 2019 Spiking neural networks implemented in dynamic neuromorphic processors are well suited for spatiotemporal feature detection and learning, for example in ultra low-power embedded intelligence and deep edge applications. Such pattern recognition networks naturally involve a combination of dynamic delay mechanisms and coincidence detection. Inspired by an
arxiv +1 more source
A biophysical observation model for field potentials of networks of leaky integrate-and-fire neurons
, 2012 We present a biophysical approach for the coupling of neural network activity as resulting from proper dipole currents of cortical pyramidal neurons to the electric field in extracellular fluid.
Graben, Peter beim, Rodrigues, Serafim
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The effect of heterogeneity on decorrelation mechanisms in spiking neural networks: a neuromorphic-hardware study [PDF]
, 2014 High-level brain function such as memory, classification or reasoning can be realized by means of recurrent networks of simplified model neurons. Analog neuromorphic hardware constitutes a fast and energy efficient substrate for the implementation of ...
Diesmann, Markus +6 more
core +5 more sources
Control over stress induces plasticity of individual prefrontal cortical neurons: A conductance-based neural simulation [PDF]
, 2012 Behavioral control over stressful stimuli induces resilience to future conditions when control is lacking. The medial prefrontal cortex(mPFC) is a critically important brain region required for plasticity of stress resilience. We found that control over stress induces plasticity of the intrinsic voltage-gated conductances of pyramidal neurons in the ...
arxiv +1 more source