Results 91 to 100 of about 2,252,502 (296)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Designing and delivering inclusive heritage tours: Good practices for engaging socially excluded audiences

open access: yesTourism
People who experience social exclusion often face barriers to participation in recreation and tourism and tend to have limited engagement with culture and heritage. Yet, both sets of activities have been linked to a range of positive outcomes.
Lynn Minnaert
doaj   +1 more source

Equity, Exclusion and Everyday Science Learning

open access: yes, 2019
Featured in the Spokes article collection Learning theory, Equity and inclusion What’s the biggest problem affecting the science centre, science museum, informal science learning and science communication sectors?
Emily Dawson
semanticscholar   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

New Exclusion for Children with Special Needs Case Study in Inclusive School in Banyumas Regency

open access: yesYinyang: Jurnal Studi Islam, Gender dan Anak
Inclusive education implemented in Banyumas Regency has attempted to provide opportunities for children with special needs to get education together with other students.
Aan Desta Riani   +2 more
doaj   +1 more source

Facebook jako źródło wykluczenia społecznego ery Web 2.0

open access: yesAdeptus, 2017
Facebook as a new source of social exclusion in Web 2.0 era Social life in the 21st century is no longer composed simply of direct communication but also of technology-mediated one.
Katarzyna Natalia Sobczak
doaj   +1 more source

Social exclusion of older persons: a scoping review and conceptual framework

open access: yesEuropean Journal of Ageing, 2016
As a concept, social exclusion has considerable potential to explain and respond to disadvantage in later life. However, in the context of ageing populations, the construct remains ambiguous.
K. Walsh, T. Scharf, N. Keating
semanticscholar   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

HACKING THE CITY A SOMEWHAT DIFFERENT MODE OF FIELD WORK

open access: yesEuropean Journal of Geography, 2012
Guerilla Gardening, Reclaim the street, Adbusting and others are characteristic forms of temporary appropriation of public spaces. Those have become a global trend.
Romy HOFMANN, Martina MEHREN
doaj  

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