Results 101 to 110 of about 337,234 (319)

High interspecific variation in nutrient excretion within a guild of closely related caddisfly species

open access: yesEcosphere, 2018
Understanding the amount of variation in functional traits between closely related species within guilds is critical for understanding links between community composition and ecosystem processes.
Jared A. Balik   +3 more
doaj   +1 more source

Schistosoma “Eggs-Iting” the Host: Granuloma Formation and Egg Excretion

open access: yesFrontiers in Immunology, 2018
Schistosomiasis is a major cause of morbidity in humans invoked by chronic infection with parasitic trematodes of the genus Schistosoma. Schistosomes have a complex life-cycle involving infections of an aquatic snail intermediate host and a definitive ...
Christian Schwartz   +3 more
doaj   +1 more source

Excretion Detection in Pigsties Using Convolutional and Transformerbased Deep Neural Networks [PDF]

open access: yesarXiv
Animal excretions in form of urine puddles and feces are a significant source of emissions in livestock farming. Automated detection of soiled floor in barns can contribute to improved management processes but also the derived information can be used to model emission dynamics.
arxiv  

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Influence of AMY1 gene copy number on salivary amylase activity changes induced by exercise in young adults

open access: yesPhysiological Reports
Human salivary amylase secretion increases in response to stress; the activity has been reported to rise significantly with high‐intensity exercise. The human salivary amylase gene (AMY1) has copy number variation, with the copy number correlating with ...
Yui Kobayashi   +3 more
doaj   +1 more source

Does Plasmodium falciparum have an Achilles' heel? [PDF]

open access: yesMalaria Chemotherapy, Control, and Elimination 3, 114 (2014). DOI: 10.4172/2090-2778.1000114, 2013
Plasmodium falciparum is the parasite that causes the most severe form of malaria. Currently, science has been established about its cellular structures, its metabolic processes, and even the molecular structures of its intrinsic membrane proteins responsible for transporting water, nutrient, and waste molecules across the parasite plasma membrane (PPM)
arxiv  

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren   +16 more
wiley   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

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