Results 61 to 70 of about 622,707 (285)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Amélioration des bilans d'excrétion d'azote dans deux exploitations laitières de la région wallonne par un suivi raisonné des rations

Biotechnologie, Agronomie, Société et Environnement, 2013
Improvements after precision dietary management of nitrogen rejection in two commercial dairy farms in Wallonia. Two dairy farms located in Pays de Herve and in Ardennes were followed at regular intervals in order to assess levels of nitrogen rejection ...
Knapp, E., Istasse, L., Hornick, JL., Dufrasne, I.   +3 more
doaj  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Low zinc status and absorption exist in infants with jejunostomies or ileostomies which persists after intestinal repair. [PDF]

, 2012
There is very little data regarding trace mineral nutrition in infants with small intestinal ostomies. Here we evaluated 14 infants with jejunal or ileal ostomies to measure their zinc absorption and retention and biochemical zinc and copper status. Zinc
Abrams, Steven A, Balay, Kimberly S, Chen, Zhensheng, Griffin, Ian J, Hawthorne, Keli M, Hicks, Penni D   +5 more
core   +4 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Effects of forage supplements on milk production and chemical properties, in vivo digestibility, rumen fermentation and N excretion in dairy cows offered red clover silage and corn silage or dry ground corn [PDF]

, 2010
peer-reviewedThis study concerned the effects of partial substitution of clover silage with high starch forages on milk production and chemical composition, in vivo digestibility, rumen fermentation pattern and nitrogen excretion of dairy cows.
Arriaga, H., Martinez-Suller, L., Merino, P., Salcedo, G.   +3 more
core  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Vascular risk factors and diabetic neuropathy [PDF]

, 2005
Background: Other than glycemic control, there are no treatments for diabetic neuropathy. Thus, identifying potentially modifiable risk factors for neuropathy is crucial.
Chaturvedi, N., Eaton, S.E.M., Fuller, J.H., Ionescu-Tirgoviste, C., Manes, C., Tesfaye, S., Ward, J.D., Witte, D.R.   +7 more
core   +1 more source

Reduction of Salmonella Shedding by Sows during Gestation in Relation to Its Fecal Microbiome

Frontiers in Microbiology, 2017
Pork meat is estimated to be responsible for 10–20% of human salmonellosis cases in Europe. Control strategies at the farm could reduce contamination at the slaughterhouse.
Guillaume Larivière-Gauthier, Alexandre Thibodeau, Ann Letellier, Étienne Yergeau, Philippe Fravalo   +4 more
doaj   +1 more source