Results 11 to 20 of about 604,131 (324)
Dasatinib is a potent enhancer for CAR T cell generation by CD3-targeted lentiviral vectors
Molecular Therapy: Methods & Clinical Development, 2023 CD3-targeted lentiviral vectors (CD3-LVs) mediate selective transduction of human T lymphocytes in vitro and in vivo while simultaneously activating the targeted cells.
Angela H. Braun +3 more
doaj +1 more source
Parameter estimation and treatment optimization in a stochastic model for immunotherapy of cancer [PDF]
, 2020 Adoptive Cell Transfer therapy of cancer is currently in full development and mathematical modeling is playing a critical role in this area. We study a stochastic model developed by Baar et al.
Coquille, Loren +2 more
core +1 more source
Frontiers in Immunology, 2021 The discovery of immune checkpoints highlights the complexity of T cell signalling during an immune response. Upon activation, T cells express several molecules to regulate their function and to prevent overactivation.
Khang Luu +9 more
doaj +1 more source
Domains with a continuous exhaustion in weakly complete surfaces [PDF]
, 2019 In previous works, G. Tomassini and the authors studied and classified complex surfaces admitting a real-analytic pluri-subharmonic exhaustion function; let $X$ be such a surface and $D\subseteq X$ a domain admitting a \emph{continuous} plurisubharmonic ...
Mongodi, Samuele, Slodkowski, Zbigniew
core +2 more sources
Kondo Lattice without Nozieres Exhaustion Effect [PDF]
, 2005 We discuss the properties of layered Anderson/Kondo lattices with metallic electrons confined in 2D xy planes and local spins in insulating layers forming chains in z direction.
+13 more
core +1 more source
Viral infections and immune modulation in bladder cancer: implications for immunotherapy [PDF]
Exploration of Targeted Anti-tumor TherapyThis review explores the intricate relationship between viral infections and Bacillus Calmette-Guerin (BCG) efficacy, emphasizing immune modulation mechanisms that may influence treatment outcomes.
Lívia Bitencourt Pascoal +8 more
doaj +1 more source
Intervening for exhaustion [PDF]
, 2006 "The search for psychosocial factors that contribute to the aetiology and course of coronary heart disease (CHD) has been an energetic, although not always fruitful, pursuit for more than half a century.
Anna C. Phillips +16 more
core +2 more sources
GeoHumanities, 2016 This experimental photo essay responds to a growing foreboding that the future has been occupied, colonized, or destroyed. It is a methodological experiment with attunement and futurity, aiming not to reattune to authentic forms of temporality or to rediscover lost forms of imagination and memory, but to make creative use of our temporal misattunements
openaire +1 more source
Clinical and Translational Medicine, 2020 Background Exhausted T cells and regulatory T cells (Tregs) comprise diverse subsets of tumor immunosuppressive microenvironment that play key roles in tumor progress. Understanding subset diversity in T cells is a critical question for developing cancer
Yanying Yang +10 more
doaj +1 more source
eLife, 2022 CD4+ T cells are critical orchestrators of immune responses against a large variety of pathogens, including viruses. While multiple CD4+ T cell subtypes and their key transcriptional regulators have been identified, there is a lack of consistent ...
Massimo Andreatta +5 more
doaj +1 more source