Results 111 to 120 of about 504,362 (312)
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Existence, uniqueness and constructive results for delay differential equations
Electronic Journal of Differential Equations, 2005 Here, we investigate boundary-value problems (BVPs) for systems of second-order, ordinary, delay-differential equations. We introduce some differential inequalities such that all solutions (and their derivatives) to a certain family of BVPs satisfy some ...
Paul W. Eloe +2 more
doaj
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Space-dependent variable-order time-fractional wave equation: Existence and uniqueness of its weak solution [PDF]
, 2022 Karel Van Bockstal +2 more
openalex +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Existence and uniqueness of the p-generalized modified error function
Electronic Journal of Differential Equations, 2020 In this article, we define a p-generalized modified error function as the solution to a non-linear ordinary differential equation of second order, with a Robin type boundary condition at x=0.
Julieta Bollati +3 more
doaj
Existence and Uniqueness Results for Nonlinear Boundary Value Problems [PDF]
, 1993 D. D. Hai, Klaus Schmitt
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Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Existence, uniqueness, and long-time behavior of linearized field dislocation dynamics [PDF]
, 2022 Amit Acharya, Marshall Slemrod
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Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source