Results 51 to 60 of about 1,366,829 (246)
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Meaning in the Context of Existential Hagiotherapy [PDF]
The aim of this thesis is to describe meaning in the context of Existential Hagiotherapy and to answer the following research question: How do hagiotherapy participants experience the existential meaning?
Nečasová, Eliška
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ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
The negative existential cycle in Bantu
Renewal of negation has received ample study in Bantu languages. Still, the relevant literature does not mention a cross-linguistically recurrent source of standard negation, i.e., the existential negator.
Devos, MaudLW2180200115676092324714-0C13-11E2-AA3C-3DCD10BDE39D +2 more
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The power of relational work in existential therapy [PDF]
The power of relational work in existential therapy Aim/Purpose: This paper aims to present some preliminary findings from a PhD research study focusing on how existential therapists define and convey their role as therapists, with a particular ...
Smith, Vicki J
core +3 more sources
The hardness of the iconic must: Can Peirce’s existential graphs assist modal epistemology? [PDF]
Charles Peirce’s diagrammatic logic - the Existential Graphs - is presented as a tool for illuminating how we know necessity, in answer to Benacerraf’s famous challenge that most “semantics for mathematics” do not “fit an acceptable epistemology”.
Legg, Catherine, C. Legg
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Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The quest for meaning in life has always constituted a big portion of literature. Having Existential dimensions that investigate the big questions of human existence such as death, isolation, freedom and meaning, some literary works like Rebecca West’s ...
Bukhari Abdullah Rasool +1 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source

