Results 51 to 60 of about 25,750 (260)
Would you exchange your soul for immortality?-existential meaning and afterlife beliefs predict mind upload approval. [PDF]
Laakasuo M +6 more
europepmc +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Making existential meaning in transition to motherhood-A scoping review
Objective: To provide a thematic overview of the existing literature on existential meaning-making related to transition to motherhood among mothers of full term born babies in Western oriented countries and to discuss the themes from a existential ...
Prinds, Christina; id_orcid +3 more
core +1 more source
Spanish Validation of the Multidimensional Existential Meaning Scale: Which Dimension of Meaning in Life Is More Associated With Psychopathology in People With Mental Disorders? [PDF]
Marco JH +5 more
europepmc +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Russian verbs BYT’ and BYVAT’: existential and non‑existential meanings [PDF]
Two Russian verbs with existential meaning are compared – byt’ and byvat’. The verb byt’ “to be” is the main existential verb in Russian: collocations existential sentences and existential verbs are translated into Russian as bytijnye predloženia “existential sentences” and bytijnye glagoly “existential verbs.” The verb byt’ is ambiguous.
openaire +1 more source
On the structure and meaning of NPs in Turkish existentials
This paper analyzes the structural and interpretive properties of Noun Phrases (NPs henceforth) in Turkish existential sentences. There are three different types of NPs, namely bare NPs, singular indefinite NPs and plural indefinite NPs, that can appear in existential structures.
Görgülü, Emrah, Görgülü, Emrah
openaire +2 more sources
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
ATTITUDE OF EXISTENTIALISM ABOUT "EXISTENTIAL DYING" AND ITS HUMANISTIC MEANING
Existentialism is the philosophy of attitudes, a step away from traditional philosophy. The stance of existentialism of "dying" is one of those attitudes. Dying is a process by which the subject loses subjectivity, leading to a loss of personality due to the disparity between material life and the spiritual life that people do not recognize.
Nguyễn Tiến Dũng +1 more
openaire +2 more sources
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source

