Results 61 to 70 of about 25,750 (260)
, 2013 It is often claimed that modern media massively return the repressed yet unavoidable fact of death, which modernity had institutionalised and placed out of sight.
Lagerkvist, Amanda,
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Existential Sentences Crosslinguistically: Variations in Form and Meaning [PDF]
Annual Review of Linguistics, 2016 Though the term “existential sentence” goes back at least as far as Jespersen (1924 , p. 155) and is used in descriptions of many languages to refer to a designated construction, it is difficult to identify exactly what these constructions have in common crosslinguistically. Following McNally (2011 , p. 1829), the term is used here to refer to sentence
openaire +2 more sources
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
, 2017 Aims: Present results from focus interviews concerning existential aspects related to the adaptation of the WHOQOL-SRPB(BREF) for Swedish adolescents.Background: Exploring existential aspects of HRQL are important when mental ill-health is increasing ...
Söderqvist, Fredrik, +1 more
core
Existential configurations : a way to conceptualise people’s meaning-making
, 2020 This paper introduces existential configuration as a concept possibly used to describe, talk about and discuss peoples’ meaning-making, not least in religious education classrooms.
Gustavsson, Caroline,
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Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
, 2017 Aims: Present results from focus interviews concerning existential aspects related to the adaptation of the WHOQOL-SRPB(BREF) for Swedish adolescents. Background: Exploring existential aspects of HRQL are important when mental ill-health is increasing ...
Melder, Cecilia A, Söderqvist, Fredrik
core
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source