Results 81 to 90 of about 252,625 (305)

The Hermeneutics of Values in the Novel A Portion of Chicken Noodles Before Dying as a Source of Existential Counseling Intervention

Bisma The Journal of Counseling
Many individuals experience confusion regarding the meaning and purpose of life due to the pressure of social comparison, making it difficult for them to fully understand themselves. This study aims to analyze the existential values in the novel Seporsi
Rahmawati, Budi Purwoko, Evi Winingsih, Bakhrudin All Habsy   +3 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Cosmic Existentialism: Existence in an Indifferent Universe

Philosophies
The problem of meaning in an apparently indifferent universe has long been a central concern of existential philosophy. Classical existentialism addressed this question by emphasizing human freedom, responsibility, and the creation of meaning in the ...
Eduardo Duque-Dussán
doaj   +1 more source

Existential and religious motifs in L.S. Vygotsky’s essay on “Hamlet” (1916)

Культурно-историческая психология, 2018
In this article existential and religious motifs in the works of young L.S. Vygotsky are considered. The specificity of the existential approach, characterized by blurring the limits of philosophy, science and art and the formation of a synthetic method ...
Chesnokova M.G.,
doaj   +1 more source

Would you exchange your soul for immortality?-existential meaning and afterlife beliefs predict mind upload approval. [PDF]

Front Psychol, 2023
Laakasuo M, Sundvall J, Francis K, Drosinou M, Hannikainen I, Kunnari A, Palomäki J.   +6 more
europepmc   +1 more source

Catalogue of Anti-Patterns for formal Ontology debugging [PDF]

, 2009
Debugging of inconsistent OWL ontologies is normally a tedious and time-consuming task where a combination of ontology engineers and domain expert is often required to understand whether the changes to be performed in order to make the OWL ontology ...
Corcho, Oscar, Roussey, C., Vilches-Blázquez, LM.   +2 more
core   +2 more sources

The Great Escape: The Role of Self-esteem and Self-related Cognition in Terror Management [PDF]

, 2015
Integrating terror management theory and objective self-awareness theory, we propose the existential escape hypothesis, which states that people with low self-esteem should be especially prone to escaping self-awareness as a distal response to thoughts
Anderson, Arnaud Wisman, Arndt, Arndt, Arndt, Asendorpf, Baldwin, Barnett, Baumeister, Becker, Blascovich, Brockner, Brown, Burke, Carver, Castano, Chatard, Cheng, Cicirelli, Davis, Davis, Dehaene, Diener, Dougherty, Du, Duval, Duval, Fazio, Fejfar, Feldman, Florian, Friedman, Goldenberg, Goldenberg, Goldenberg, Govern, Greenberg, Greenberg, Greenberg, Greenberg, Greenberg, Greenberg, Greenberg, Harlow, Harmon-Jones, Hayes, Hayes, Heatherton, Heatherton, Heine, Higgins, Hirschberger, Hull, Hull, Hull, Ickes, Jamie L. Goldenberg, Jessop, Juhl, Kesebir, Kouider, Kral, Landau, Landau, Mann, Maris, Martens, McGregor, Menard, Milgram, Mor, Moskalenko, Mullen, Muraven, Muraven, Nathan Heflick, Phillips, Pilling, Polivy, Pyszczynski, Pyszczynski, Pyszczynski, Richter, Rosenberg, Rosenblatt, Routledge, Routledge, Schimel, Schmeichel, Schmeichel, Shrout, Silvia, Silvia, Silvia, Silvia, Snow, Steele, Stein, Tafarodi, Taubman Ben-Ari, Taylor, Vaes, Vlahov, Watson, Wegner, Wegner, Wegner, Wentura, Wicklund, Wicklund, Wisman, Wisman, Wisman, Yang, Zimbardo   +114 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Existential concerns among young adults with psychotic vulnerability in mental health care: a qualitative study in the Netherlands

BMC Psychiatry
Background Young adults with psychotic vulnerability are dealing with disrupting experiences early in life, often with far-reaching or even lifelong impacts. These experiences can lead to existential questions during young adulthood. Identity realization
Marlous L. D. de Vries, Pauline Janse, Christa W. Anbeek, Arjan W. Braam   +3 more
doaj   +1 more source

Spanish Validation of the Multidimensional Existential Meaning Scale: Which Dimension of Meaning in Life Is More Associated With Psychopathology in People With Mental Disorders? [PDF]

Front Psychiatry, 2022
Marco JH, García-Alandete J, Pérez Rodríguez S, Guillén V, Baños RM, Tormo-Irun MP.   +5 more
europepmc   +1 more source