Results 61 to 70 of about 15,412 (264)

The Hermeneutics of Values in the Novel A Portion of Chicken Noodles Before Dying as a Source of Existential Counseling Intervention

open access: yesBisma The Journal of Counseling
Many individuals experience confusion regarding the meaning and purpose of life due to the pressure of social comparison, making it difficult for them to fully understand themselves. This study aims to analyze the existential values in the novel Seporsi
Rahmawati   +3 more
doaj   +1 more source

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa   +3 more
wiley   +1 more source

Would you exchange your soul for immortality?-existential meaning and afterlife beliefs predict mind upload approval. [PDF]

open access: yesFront Psychol, 2023
Laakasuo M   +6 more
europepmc   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda   +15 more
wiley   +1 more source

Existential concerns among young adults with psychotic vulnerability in mental health care: a qualitative study in the Netherlands

open access: yesBMC Psychiatry
Background Young adults with psychotic vulnerability are dealing with disrupting experiences early in life, often with far-reaching or even lifelong impacts. These experiences can lead to existential questions during young adulthood. Identity realization
Marlous L. D. de Vries   +3 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Bergman’s Cinema in the mirror of Existential Philosophies [PDF]

open access: yesحکمت و فلسفه
This paper presents analysis of the cinema of Ingmar Bergman through the lens of existential philosophies. Bergman, recognized as one of the Prominent and Influential Filmmakers of the 20th century, masterfully uses the language of cinema to explore the ...
Ali Arbabi, Mohammad Raayat Jahromi
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

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