Results 31 to 40 of about 15,271 (203)
Advanced Science, EarlyView.This study demonstrates that transcription factor androgen receptor (AR) directly binds the LF promoter, driving lactoferrin overexpression to promote ferritin (FTH1/FTL) upregulation and inhibit p53‐ALOX12‐mediated ferroptosis in prostate cancer. Lactoferrin could be a new potential therapeutic target in prostate cancer.
Can Liu +18 more
wiley +1 more source
Journal of the Dow University of Health Sciences, 2007 Sjogen's syndrome is an autoimmune and a chronic inflammatory disorder characterized by the infilrration of the exocrine glands particulary the lacrimal and the salivary glands by the lymphocytes and the plasma cells resulting in xerostomia and ...
Pyar Ali Fazel +3 more
doaj +2 more sources
Molecules, 2021 The African weaver ant, Oecophylla longinoda, is used as a biological control agent for the management of pests. The ant has several exocrine glands in the abdomen, including Dufour’s, poison, rectal, and sternal glands, which are associated with ...
Bethelihem Mekonnen +6 more
doaj +1 more source
Advanced Science, EarlyView.Tumor‐derived lactate activates PSCs through MCT1‐mediated Vps34 lactylation and autophagy. These activated PSCs secrete CXCL9/10, upregulating PD‐1 on CD8+ T cells via the CXCR3/STAT3 axis to foster immunosuppression. Disrupting this metabolic crosstalk by targeting MCT1 effectively sensitizes pancreatic cancer to PD‐1 blockade, presenting a promising
Wenfeng Zhuo +14 more
wiley +1 more source
Marginal Zone B-Cell Lymphoma of the Lacrimal Gland Secondary to Sjogren’s Syndrome
Türk Oftalmoloji Dergisi, 2014 Sjogren’s syndrome is a chronic, autoimmune, inflammatory disease which can affect all exocrine glands, particularly the salivary and lacrimal glands, causing dryness of the mouth and eyes.
Hatice Deniz İlhan +4 more
doaj +1 more source
CD8+ T Lymphocytes: Crucial Players in Sjögren’s Syndrome
Frontiers in Immunology, 2021 Primary Sjögren’s syndrome (pSS) is a chronic autoimmune disease associated with damage to multiple organs and glands. The most common clinical manifestations are dry eyes, dry mouth, and enlarged salivary glands.
Huimin Zhou +5 more
doaj +1 more source
Animal Models and Experimental Medicine, EarlyView.Directed differentiation of pluripotent stem cells into functional pancreatic β cells have emerged as a promising strategy for the radical treatment of type 1 diabetes, with preclinical and early clinical evidence demonstrating reversal of hyperglycemia and insulin independence.
Zifan Li, Yu Kang, Yuyu Niu
wiley +1 more source
Exocrine glands of Schwarziana quadripunctata (Hymenoptera, Apinae, Meliponini)
Brazilian Journal of BiologyThis article describes the location, anatomy, histology and ontogeny of adult Schwarziana quadripunctata exocrine glands. These glands appear either as individualized organs (salivary gland system and Dufour gland) or as epidermis differentiation ...
C. CRUZ-LANDIM, R. D. REGINATO
doaj +1 more source
Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles
Advanced NanoBiomed Research, EarlyView.This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley +1 more source
MicroRNA in Sjögren’s Syndrome: Their Potential Roles in Pathogenesis and Diagnosis
Journal of Immunology Research, 2018 Sjögren’s syndrome (SS) or sicca syndrome was described by Swedish ophthalmologist Sjögren in the year 1933 for the first time. The etiology of the SS is multifunctional and includes a combination of genetic predisposition and environmental as well as ...
M. Reale +5 more
doaj +1 more source