Results 151 to 160 of about 151,391 (333)
Human brain matters: Navigating the neuropathology of COVID‐19
Brain Pathology, EarlyView.Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland +4 more
wiley +1 more source
Tracking Ca2+-dependent and Ca2+-independent conformational transitions in syntaxin 1A during exocytosis in neuroendocrine cells [PDF]
, 2013 Dafna Greitzer-Antes +5 more
openalex +1 more source
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Aim To characterise the metabolic benefits of a GLP‐1/apelin hybrid peptide, namely exendin‐4‐linker‐apelin (ELA), and associated acylated forms, including ELA‐Lys12(γGluPal), ELA‐Lys27(γGluPal) and ELA‐Lys38(γGluPal). Methods Concentration‐ and receptor‐dependent effects of the peptides on insulin secretion and beta‐cell turnover were ...
Ananyaa Sridhar +5 more
wiley +1 more source
Imaging analysis reveals mechanistic differences between first- and second-phase insulin exocytosis [PDF]
, 2007 Mica Ohara‐Imaizumi +10 more
openalex +1 more source
The FEBS Journal, EarlyView.Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley +1 more source
V-ATPase activity in the TGN/EE is required for exocytosis and recycling in Arabidopsis [PDF]
, 2015 Yu Luo +17 more
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A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer
The FEBS Journal, EarlyView.Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou +4 more
wiley +1 more source
Variability in intracellular localization of D‐amino acid oxidase in choroid plexus epithelial cells
The FEBS Journal, EarlyView.D‐amino acid oxidase (DAO) in choroid plexus epithelial cells (CPECs) shows vesicle‐like localization by histological and super‐resolution analyses. DAO colocalizes with peroxisomal, Golgi, endosomal, lysosomal, autophagosomal, and exosomal markers, indicating diverse subcellular distribution. This suggests DAO is transported within CPECs to metabolize
Koji Ono +3 more
wiley +1 more source
Evidence that a GABAA-Like Receptor is Involved in Progesterone-Induced Acrosomal Exocytosis in Mouse Spermatozoa1 [PDF]
, 1995 Qi‐Xian Shi, Eduardo R. S. Roldán
openalex +1 more source