Characterization of hormone and protein release from alpha-toxin- permeabilized chromaffin cells in primary culture [PDF]
, 1986 Addition of Staphylococcus aureus alpha-toxin to adult bovine chromaffin cells maintained in primary culture causes permeabilization of cell membrane as shown by the release of intracellular 86Rb+.
Ahnert-Hilger, G. +4 more
core
Evaluation of the role of inositol trisphosphate in IgE-dependent exocytosis [PDF]
, 1990 Galia Gat‐Yablonski +1 more
openalex +1 more source
A Biomimetic Micro‐Nano System Maximizing ‘Active Transport and Retention’ Effect in Solid Tumors
Small, EarlyView.The Active Transport and Retention (ATR) strategy is realized using a biomimetic micro‐nano system (PG@BAM‐LRC), achieving superior tumor accumulation and efficacy in low‐EPR pancreatic tumors. Platelet (PG)‐derived microcarriers enable tumor‐homing and MMP‐9‐responsive release of nanoliposomes (LRC), while berbamine (BAM) promotes transendothelial ...
Kaiyun Yang +4 more
wiley +1 more source
Impact of Sorting and Catch Media on Porcine Sperm Motility, Capacitation, and Viability
Andrology, EarlyView.ABSTRACT Background Fluorescence‐activated cell sorting (FACS) has emerged as a powerful tool for selecting spermatozoa of a desired population of fluorescent biomarkers, offering potential applications in reproductive biology and agriculture. However, concerns remain regarding sorting‐induced physiological alterations that could compromise spermatozoa
Tyler Weide, Juan Steibel, Karl Kerns
wiley +1 more source
Andrology, EarlyView.ABSTRACT Background Challenges in establishing clinical conventional in vitro fertilization (IVF) in horses include variation in sperm and oocyte quality, which can be affected by mare age. Extended preincubation of stallion spermatozoa has resulted in successful IVF.
Raul A. Gonzalez‐Castro +6 more
wiley +1 more source
Brain Pathology, EarlyView.Untargeted multiomic profiling of cerebrospinal fluid reveals that proteomic, but not lipidomic, signatures robustly distinguish ALS patients from controls and stratify individuals by survival, highlighting marked molecular differences between short survival and long survival disease.
Sergio Roca‐Pereira +19 more
wiley +1 more source
Consciousness operates beyond the timescale for discerning time intervals: implications for Q-mind theories and analysis of quantum decoherence in brain [PDF]
, 2003 This paper presents in details how the subjective time is constructed by the brain cortex via reading packets of information called "time labels", produced by the right basal ganglia that act as brain timekeeper.
Georgiev, Danko
core
Munc18-2, but not Munc18-1 or Munc18-3, controls compound and single-vesicle–regulated exocytosis in mast cells [PDF]
, 2018 Berenice A. Gutierrez +13 more
openalex +1 more source
Associations between TMEM106B C‐terminal fragment aggregation, age, and TDP‐43 or tau pathology
Brain Pathology, EarlyView.TMEM106B C‐terminal fragment (CTF) aggregation represents an age‐associated, common, diffuse phenomenon emerging after midlife with a weak association with TDP‐43 or tau pathology. These findings suggest that TMEM106B fibrillization may define a distinct axis of protein aggregation in the aging human brain. Abstract Transmembrane protein 106B (TMEM106B)
Albert Acewicz +5 more
wiley +1 more source