Protocol for the detection of large dense-core vesicle exocytosis using an automated image-processing algorithm. [PDF]
Makam A +5 more
europepmc +1 more source
Fluorescent Cargo Proteins in Pancreatic β-Cells: Design Determines Secretion Kinetics at Exocytosis [PDF]
Darren J. Michael +6 more
openalex +1 more source
Trafficking and potentiation of Nav1.7 and Nav1.8 channels are mediated by IQGAP1
Abstract figure legend IQGAP1 binds to the voltage‐gated Nav1.7 and Nav1.8 channels and TRPA1 channels in sensory neurons. Inflammatory mediators (IM), including PGE2 and TNFα, released during nerve injury and inflammation activate intracellular signalling messengers such as PKA, p38 MAPK and Cdc42 through their respective receptors.
Xuming Zhang +2 more
wiley +1 more source
Lysosomal exocytosis by macrophages as a druggable mechanism for anti-inflammatory clearance of dead adipocytes in adipose tissue. [PDF]
Wehr R +5 more
europepmc +1 more source
Fasudil perfusion in the NAc increased basal extracellular serotonin but not dopamine, and suppressed depolarization‐evoked release of both. In contrast, KD025 showed minimal effects on basal levels and selectively suppressed evoked serotonin release. ABSTRACT Recent studies have indicated that the Rho GTPase family and Rho‐kinases are associated with ...
Rinako Tanaka +8 more
wiley +1 more source
PAC regulates endo-, and exocytosis, and lysosomal-mitochondrial stress signaling in human mast cells. [PDF]
Melek K +8 more
europepmc +1 more source
Peritoneal fluid modulates the sperm acrosomal exocytosis induced by N-acetylglucosaminyl neoglycoprotein [PDF]
Eduardo Pandolfi Passos +6 more
openalex +1 more source
ABSTRACT Cognitive impairments are important therapeutic targets in epilepsy medication; however, effective pharmacological treatments for epilepsy patients with comorbid cognitive impairment have not been established. Effects of chronic administration of MK‐801 (noncompetitive NMDA receptor inhibitor), memantine (low‐affinity extrasynaptic‐NMDA ...
Motohiro Okada +3 more
wiley +1 more source
Reduced late endosome/lysosome function promotes SLE through chronic PI3K activity and SHP-1/SHIP-1 defects. [PDF]
Kang S +13 more
europepmc +1 more source

