Journal of Cutaneous Pathology, Volume 53, Issue 12, Page 1080-1084, December 2026.ABSTRACT Adult‐onset Still's disease (AOSD) is an auto inflammatory disorder with a variable clinical presentation, and without a pathognomonic diagnostic test, characterized by high spiking fever, arthralgia/arthritis, a suggestive skin rash, elevated white blood cell count 10 G/L (> 80% neutrophils), elevated ferritin, with glycosylated ferritin < 20%
M. Nordmann +7 more
wiley +1 more source
Lutein Attenuates Lipid Accumulation in Association with TFEB Nuclear Translocation and Autophagy-Lysosomal Responses in a Cellular Model of Hepatic Steatosis. [PDF]
Antioxidants (Basel)Saud F +6 more
europepmc +1 more source
International Journal of Laboratory Hematology, Volume 48, Issue 6, Page 1464-1471, December 2026.ABSTRACT Introduction Heparin‐induced thrombocytopenia (HIT) is a rare but potentially life‐threatening, immune‐mediated adverse reaction to heparin. PF4‐dependent immunoassays are sensitive screening tests, but they detect both platelet‐activating and nonactivating antibodies; therefore, positive results require interpretation in clinical context and,
Elvira Maličev +4 more
wiley +1 more source
Multimodal Imaging Reveals Rapid Catecholamine Uptake and Release by Neutrophils. [PDF]
Adv Sci (Weinh)Mohr J +19 more
europepmc +1 more source
New Phytologist, Volume 252, Issue 5, Page 2006-2023, December 2026.Schematics of ΔSPPbALE‐induced disruption of plant endomembrane trafficking impairs both preinvasive and postinvasive immunity against filamentous fungi and facilitates intracellular colonization by Plasmodiophora brassicae. Summary Plasmodiophora brassicae, an intracellular biotrophic protist that causes clubroot in crucifers, extensively alters the ...
Musharaf Hossain +4 more
wiley +1 more source
The Lysosomal Clock: Are We Only as Old as Our Lysosomes?
Traffic, Volume 27, Issue 4, December 2026.The lysosomal clock of aging. Aging is associated with lysosomal accumulation of glycerophosphodiesters (GPDs) and cystine, alongside remodeling of bis(monoacylglycero)phosphate (BMP). This conserved metabolic signature predicts chronological age, is attenuated by caloric restriction in peripheral tissues, and is prominent in brain microglia and ...
Alexis Diaz Vegas, Thierry Galli
wiley +1 more source
Comparison of PBS-Caffeine and Caffeine Buffers for Inhibiting Exocytosis During Horseshoe Crab Blood Collection and Improving the Yield of Limulus Amebocyte Lysate (LAL) for Endotoxin Detection. [PDF]
Int J Mol SciZhang J, Zhang S, Zhang M.
europepmc +1 more source
Beyond Membrane Fusion: SNARE Proteins as Regulators of Signaling and Gene Expression
Traffic, Volume 27, Issue 4, December 2026.Regulation of gene expression by SNAREs. Some SNAREs, including alternatively spliced isoforms, may access the nucleus where they perform various regulatory activities. These SNAREs may act as transcriptional activators or mediate/participate in the transport of transcription factors to the nucleus.
Clémentine Roux, Albert Descoteaux
wiley +1 more source
Endometriosis disrupts oocyte metabolism and cortical granule function, impairing fertilization. [PDF]
Reprod Biol EndocrinolKlinsky OG +4 more
europepmc +1 more source
Stimuli‐Responsive Lipid‐Based Nanocarriers for Antimicrobial Therapy
Advanced Therapeutics, Volume 9, Issue 11, November 2026.This manuscript demonstrated, through a scoping review of the literature, that modifying lipid nanocarriers with organic and inorganic excipients is a promising alternative to increase in vitro drug release of antimicrobial compounds under the studied stimulus and significantly enhance in vitro and in vivo antimicrobial activity compared to isolated ...
Brenda Maria Silva Bezerra +5 more
wiley +1 more source