Results 241 to 250 of about 151,391 (333)

Mitochondrial Homeostasis in Pancreatic β Cell Function: Mechanisms and Therapeutic Targets for Diabetes

Journal of Diabetes, Volume 18, Issue 5, May 2026.
This review highlights mitochondrial dysfunction as a central driver of pancreatic β cell failure in diabetes, caused by disrupted mitochondrial quality control (MQC), oxidative stress, and impaired organelle communication. Emerging therapies, such as DRAK2 inhibitors and metabolic reprogramming agents, show promise in restoring β cell function by ...
Ruihan Li, Bingqian Zhang, Yuxin Zhang, Yang Yang, Yuting Lu, Jingya Li   +5 more
wiley   +1 more source

Progranulin-driven lysosomal acidification facilitates exocytosis of PHEV-hijacked lysosomes for viral release. [PDF]

mBio
Wang Z, Chen Y, He W, Liu Y, Jiao Y, Wang G, Guan J, Zhao K, Zhang Q, Gao F, Li Z, Lan Y.   +11 more
europepmc   +1 more source

Endocytosis and exocytosis of nanoparticles in mammalian cells

, 2014
Ji Ho Park, Nuri Oh
openalex   +2 more sources

Urine‐Derived iPSC Neurospheres Uncover Proteomic Correlates of Clinical Severity in Dravet Syndrome

Journal of Neurochemistry, Volume 170, Issue 5, May 2026.
Urine epithelial cells from Dravet syndrome (DS) patients carrying distinct SCN1A variants were reprogrammed into induced pluripotent stem cells (iPSCs) and differentiated into neural stem cells (NSCs) to generate patient‐derived neurospheres. Three neurosphere lines were analyzed in biological triplicates using isobaric quantitative proteomics ...
Michele Martins, Guillaume Nugue, Andrey Aguiar, Leticia R. Q. Souza, Paulo V. Abrantes, Julia Rodrigues Trajano, Mariana Stelling, Magno Junqueira, Stevens Rehen, Marília Zaluar P. Guimarães   +9 more
wiley   +1 more source

Measuring the Dynamic Nanometric Contact Radius of a Single Microdroplet on an Electrified Microinterface

Angewandte Chemie, Volume 138, Issue 18, 27 April 2026.
Electrochemical measurements as single aqueous microdroplets collide with electrode interfaces reveal nanoscale wetting dynamics. By tuning electrostatic repulsion, we control contact formation and probe surface interactions well beyond the optical diffraction limit.
Kathryn J. Vannoy, Jeffrey Dick, Marc Koper   +2 more
wiley   +2 more sources

Calcium-sensitive synaptotagmin 11-lipid interaction modulates exo-endocytosis. [PDF]

Nat Commun
Wu X, Yao J, Huo J, Hu S, Wang B, Li Z, Pei Y, Fan H, Zhan S, Huang R, Kang X, Ma C, Lai Y, Han J, Jiao L, Song Q, Wang C, Xu H.   +17 more
europepmc   +1 more source

Exocytosis of D-Aspartate from INS-1E Clonal .BETA. Cells

, 2007
Masafumi Iharada, Miki Hiasa, Ayumi Kobara, Yoshinori Moriyama   +3 more
openalex   +2 more sources

Molecular insights into electroreceptor ribbon synapses from differential gene expression in sturgeon lateral line organs

Journal of Anatomy, Volume 248, Issue 5, Page 784-805, May 2026.
The expression of various genes involved in synapse development, stability and/or function was studied in developing mechanosensory neuromasts and electrosensory ampullary organs in sterlet sturgeon. Most were shared, including Slc17a8, Slc1a3 and Nrxn3, but Cbln18 was neuromast‐restricted and Tulp1 was ampullary organ‐restricted.
Alexander S. Campbell, Martin Minařík, David Buckley, Tanmay Anand, David Gela, Martin Pšenička, Clare V. H. Baker   +6 more
wiley   +1 more source

A Super‐Pangenome for Cultivated Citrus Reveals Evolutive Features During the Allopatric Phase of Their Reticulate Evolution

Plant Biotechnology Journal, Volume 24, Issue 5, Page 3345-3367, May 2026.
Structure of the cultivated citrus super‐pangenome. ABSTRACT The main genetic diversity observed in cultivated citrus results from a reticulate evolution involving four ancestral taxa whose radiation occurred in allopatry. In such context, GWAS analysis, genome diversity and transcriptomic studies will be significantly enhanced through pangenome ...
Gaetan Droc, Delphine Giraud, Caroline Belser, Karine Labadie, Simone Duprat, Corinne Cruaud, Benjamin Istace, Fredson Dos Santos Menezes, Edson Mario de Andrade Silva, Franck Curk, Gilles Costantino, Alexandre Soriano, Pierre Mournet, Alexis Dereeper, Maëva Miranda, Elodie Marchi, Sylvain Santoni, Raner José Santana Silva, Stéphanie Sidibe‐Bocs, François Luro, Nathalie Choisne, Florian Maumus, Barbara Hufnagel, Fabienne Micheli, Patrick Wincker, Jean‐Marc Aury, Arnaud Lemainque, Patrick Ollitrault   +27 more
wiley   +1 more source

Cochlear Amplification Modulates Synaptic Transmission at the Endbulb of Held Synapse in the Cochlear Nucleus. [PDF]

J Neurosci
Wang F, Li Y, Li GL.
europepmc   +1 more source