Results 111 to 120 of about 838,175 (338)
ExonThe golden shower tree, Cassia fistula, is a botanical symbol of persistence, providing aesthetic appeal and sophisticated ecological dynamics. As the climate change specter looms, this paper delves into the delicate interplay between changing climatic ...
Shiva S +4 more
doaj +1 more source
A new transcript in the TCRB locus unveils the human ortholog of the mouse pre-Dß1 promoter [PDF]
, 2017 Introduction: While most transcripts arising from the human T Cell Receptor locus reflect fully rearranged genes, several germline transcripts have been identified. We describe a new germline transcript arising from the human TCRB locus.
Abarrategui +33 more
core +2 more sources
In Vivo Recognition of a Vertebrate Mini-Exon as an Exon-Intron-Exon Unit
Molecular and Cellular Biology, 1993 Very small vertebrate exons are problematic for RNA splicing because of the proximity of their 3' and 5' splice sites. In this study, we investigated the recognition of a constitutive 7-nucleotide mini-exon from the troponin I gene that resides quite close to the adjacent upstream exon.
D A, Sterner, S M, Berget
openaire +3 more sources
The complete local genotype–phenotype landscape for the alternative splicing of a human exon
Nature Communications, 2016 The properties of genotype–phenotype landscapes are crucial for understanding evolution but are not characterized for most traits. Here, we present a >95% complete local landscape for a defined molecular function—the alternative splicing of a human exon (
P. Julien +4 more
semanticscholar +1 more source
Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte +13 more
wiley +1 more source
ExonLipopolysaccharides consist of a hydrophilic-polysaccharide region and a hydrophobic lipid compound known as lipid A. LPS has been reported to cause concentration-dependent agglutination of human RBCs. In this study, the HAP-Hot Aqueous-Phenol Extraction
Logesh Radhakrishnan +3 more
doaj +1 more source
Organization and sequence of the gene encoding the human acrosin-trypsin inhibitor (HUSI-II) [PDF]
, 1993 A complete cDNA encoding the acrosin-trypsin inhibitor, HUSI-II, was used as a probe to isolate genomic clones from a human placenta library. Three clones which cover the entire HUSI-II gene were isolated and characterized.
Abelson +28 more
core +1 more source
Plug-and-play genetic access to drosophila cell types using exchangeable exon cassettes.
Cell Reports, 2015 Genetically encoded effectors are important tools for probing cellular function in living animals, but improved methods for directing their expression to specific cell types are required.
F. Diao +9 more
semanticscholar +1 more source
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
ExonBackground Gestational malaria has been defined as the presence of Plasmodium spp. in maternal peripheral blood or the finding of the parasite in the placenta.
Evaris Paddy Nchianang Fonyuy +5 more
doaj +1 more source