Results 91 to 100 of about 14,025 (272)
mBio, 2021 Regulatory RNAs have emerged as ubiquitous gene regulators in all bacterial species studied to date. The combination of sequence-specific RNA interactions and malleable RNA structure has allowed regulatory RNA to adopt different mechanisms of gene ...
Daniel G. Mediati +2 more
doaj +1 more source
Regulation of tomato fruit ripening [PDF]
, 2009 Fruit ripening is a sophisticatedly orchestrated developmental process, unique to plants, that results in major physiological and metabolic changes, ultimately leading to fruit decay and seed dispersal.
Bouzayen, Mondher +4 more
core +2 more sources
Structural and biochemical studies of the 5′→3′ exoribonuclease Xrn1 [PDF]
Nature Structural & Molecular Biology, 2011 The 5'→3' exoribonucleases (XRNs) have important functions in transcription, RNA metabolism and RNA interference. The structure of Rat1 (also known as Xrn2) showed that the two highly conserved regions of XRNs form a single, large domain that defines the active site of the enzyme.
Kehui Xiang +5 more
openaire +3 more sources
Nature Communications, 2018 The mitochondrial RNA degradosome (mtEXO) plays an essential role in the regulation of mitochondrial gene expression and is composed of the 3′-to-5′ exoribonuclease Dss1 and the helicase Suv3.
Michal Razew +12 more
doaj +1 more source
Remdesivir for the Treatment of COVID-19: A Systematic Review of the Literature [PDF]
, 2020 In March 2020, the World Health Organization declared the spread of SARS-CoV-2 a global pandemic. To date, coronavirus disease-2019 (COVID-19) has spread to over 200 countries, leading to over 1.6 million cases and over 99,000 deaths. Given that there is
Aly, Besma +9 more
core
A novel role for the 3′-5′ exoribonuclease Dis3L2 in controlling cell proliferation and tissue growth [PDF]
, 2016 In a complex organism, cell proliferation and apoptosis need to be precisely controlled in order for tissues to develop correctly. Excessive cell proliferation can lead to diseases such as cancer. We have shown that the exoribonuclease Dis3L2 is required
Benjamin P. Towler +5 more
core +2 more sources
MAC5, an RNA-binding protein, protects pri-miRNAs from SERRATE-dependent exoribonuclease activities
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance In Arabidopsis, MAC5, a component of the conserved MOS4-associated complex, is required for development and immunity. This study shows that MAC5 interacts with Serrate (SE) and the stem loop of pri-miRNAs, facilitates pri-miRNA processing ...
Shengjun Li +6 more
semanticscholar +1 more source
The FEBS Journal, Volume 292, Issue 11, Page 2715-2736, June 2025.The silencing of transposable elements is mediated by piRNAs through post‐transcriptional and transcriptional regulation. In Drosophila, piRNAs are processed within unique non‐membrane structures: nuage in germline cells and Yb bodies in somatic gonadal cells.
Ritsuko Suyama, Toshie Kai
wiley +1 more source
A noncoding RNA produced by arthropod-borne flaviviruses inhibits the cellular exoribonuclease XRN1 and alters host mRNA stability [PDF]
, 2012 All arthropod-borne flaviviruses generate a short noncoding RNA (sfRNA) from the viral 3′ untranslated region during infection due to stalling of the cellular 5′-to-3′ exonuclease XRN1.
Akira, Shizuo +6 more
core +1 more source
RNA: A publication of the RNA Society, 2018 N6-methyladenosine (m6A) modifications in RNAs play important roles in regulating many different aspects of gene expression. While m6As can have direct effects on the structure, maturation, or translation of mRNAs, such modifications can also influence ...
Jens Kretschmer +5 more
semanticscholar +1 more source