Results 71 to 80 of about 3,047 (148)

Double‐Stranded DNA Reduces dsRNA Degradation in the Saliva and Significantly Enhanced RNAi‐Mediated Gene Silencing in Halyomorpha halys

open access: yesAdvanced Biology, Volume 9, Issue 9, September 2025.
The invasive pest Halyomorpha halys causes significant crop losses requiring innovative pest control strategies such as RNA interference (RNAi). However, oral RNAi is largely ineffective in H. halys. This study shows that double‐stranded DNA (dsDNA) stabilizes dsRNA in saliva by inhibiting a highly expressed nuclease.
Venkata Partha Sarathi Amineni   +2 more
wiley   +1 more source

RNA‐binding proteins orchestrating immunity in plants

open access: yesThe Plant Journal, Volume 123, Issue 5, September 2025.
SUMMARY RNA‐binding proteins (RBPs) direct the function and fate of RNA throughout the RNA lifecycle and play important roles in plant immunity, orchestrating the post‐transcriptional reprogramming of the transcriptome following induction of plant immune responses, a process that we term ‘RBP‐mediated immunity’. Although the importance of specific RBPs
Marcel Bach‐Pages   +4 more
wiley   +1 more source

Performance of Long‐Read Single‐Molecule Real‐Time Sequencing for SARS‐CoV‐2 Genotyping in Clinical Samples

open access: yesJournal of Medical Virology, Volume 97, Issue 8, August 2025.
ABSTRACT Due to the continuous genetic evolution of SARS‐CoV‐2, numerous variants have emerged and different whole genome sequencing techniques, necessary for accurate virus typing, have been developed. In this study, we evaluated the performance of PacBio single‐molecule real‐time (SMRT) sequencing for SARS‐CoV‐2 typing.
Pauline Trémeaux   +6 more
wiley   +1 more source

Defining the Parameters for Sorting of RNA Cargo Into Extracellular Vesicles

open access: yesJournal of Extracellular Vesicles, Volume 14, Issue 7, July 2025.
ABSTRACT Extracellular vesicles (EVs) are small particles that are released by cells and mediate cell–cell communication by transferring bioactive molecules such as RNA. RNA cargo of EVs, including coding and non‐coding RNAs, can change the behaviour of recipient cells, affecting processes including gene expression, proliferation, and Fapoptosis ...
Ahmed Abdelgawad   +6 more
wiley   +1 more source

RNA Sequencing Identifies New RNase III Cleavage Sites in Escherichia coli and Reveals Increased Regulation of mRNA

open access: yesmBio, 2017
Ribonucleases facilitate rapid turnover of RNA, providing cells with another mechanism to adjust transcript and protein levels in response to environmental conditions. While many examples have been documented, a comprehensive list of RNase targets is not
Gina C. Gordon   +2 more
doaj   +1 more source

Conserved mechanism of Xrn1 regulation by glycolytic flux and protein aggregation

open access: yesHeliyon
The regulation of gene expression in eukaryotes relies largely on the action of exoribonucleases, evolutionarily conserved enzymes that digest decapped messenger RNAs in the 5’-3’ direction.
Satyendra Mondal   +3 more
doaj   +1 more source

Xrn1 Exoribonuclease—An Intrinsic Marker of Yeast Population Growth

open access: yesFrontiers in Bioscience-Elite
Background: Xrn1 exoribonuclease is the major mRNA degradation enzyme in Saccharomyces cerevisiae. In exponentially growing cells, Xrn1 is localised in the yeast cells and directs the degradation of mRNA molecules. Xrn1 is gradually deposited and presumably inactivated in the processing bodies (P-bodies) as the yeast population ages.
Tomas Vomastek, Tomas Grousl
openaire   +3 more sources

Exoribonuclease-resistant RNAs in tick-borne flaviviruses

open access: yes
Tick-borne flaviviruses (TBF) are a group of emerging and re-emerging pathogens that affect large geographic regions, including Europe, Asia, North America, and Africa, posing a major public health threat. A critical aspect of their molecular biology and pathology is the presence of evolutionarily conserved functional RNAs in their 3’ untranslated ...
Sidl, Leonhard   +3 more
openaire   +1 more source

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