Results 81 to 90 of about 83,398 (334)
The exosome journey: from biogenesis to uptake and intracellular signalling
Cell Communication and Signaling, 2021 The use of exosomes in clinical settings is progressively becoming a reality, as clinical trials testing exosomes for diagnostic and therapeutic applications are generating remarkable interest from the scientific community and investors.
Sonam Gurung +3 more
doaj +1 more source
TLR-exosomes exhibit distinct kinetics and effector function [PDF]
arXiv, 2016 The innate immune system is vital to rapidly responding to pathogens and Toll-like receptors (TLRs) are a critical component of this response. Nanovesicular exosomes play a role in immunity, but to date their exact contribution to the dissemination of the TLR response is unknown.
arxiv
Tetherin is an exosomal tether
eLife, 2016 Exosomes are extracellular vesicles that are released when endosomes fuse with the plasma membrane. They have been implicated in various functions in both health and disease, including intercellular communication, antigen presentation, prion transmission, and tumour cell metastasis.
Edgar, James R +4 more
openaire +7 more sources
Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis
FEBS Open Bio, EarlyView.Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu +6 more
wiley +1 more source
Cancer NanotechnologyBackground Major therapeutic developments have been made in the prevention of head and neck cancer (HNC), and crucial measures have been implemented for the survival of patients.
Kaumudi Pande +2 more
doaj +1 more source
PLoS Genetics, 2020 Accurate target recognition in transcript degradation is crucial for regulation of gene expression. In the fission yeast Schizosaccharomyces pombe, a number of meiotic transcripts are recognized by a YTH-family RNA-binding protein, Mmi1, and selectively ...
Yuichi Shichino +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran +3 more
wiley +1 more source
Bioactive Materials, 2022 Although advances in protein assembly preparation have provided a new platform for drug delivery during tissue engineering, achieving long-term controlled exosome delivery remains a significant challenge. Diffusion-dominated exosome release using protein
Muyang Sun +11 more
doaj
Biophysical characterization of membrane phase transition profiles for the discrimination of Outer Membrane Vesicles (OMVs) from Escherichia coli grown at different temperatures [PDF]
arXiv, 2019 Dynamic Light Scattering (DLS), Small Angle X-ray Scattering (SAXS) and Transmission Electron Microscopy (TEM) are physical techniques widely employed to characterize the morphology and the structure of vesicles such as liposomes or human extracellular vesicles (exosomes). Bacterial extracellular vesicles are similar in size to human exosomes, although
arxiv
Advanced Biology, EarlyView.Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi +4 more
wiley +1 more source