Results 81 to 90 of about 168,932 (404)

Calcium phosphate particles stimulate interleukin-1β release from human vascular smooth muscle cells: A role for spleen tyrosine kinase and exosome release [PDF]

, 2017
Aims: Calcium phosphate (CaP) particle deposits are found in several inflammatory diseases including atherosclerosis and osteoarthritis. CaP, and other forms of crystals and particles, can promote inflammasome formation in macrophages leading to caspase ...
Afonina, Alexander N. Kapustin, Alfaidi, Bailet, Baroja-Mazo, Bautista Nino, Bennett, Burton, Catherine M. Shanahan, Chen, Cilla, Coopman, Cossetti, Cullen, Cunningham, Dautova, Diane Proudfoot, Duewell, Ehara, Erlinge, Ewence, Feil, Fuerst, Furman, Gross, Hanneke Okkenhaug, Hendriks, Hilgendorf, Hutcheson, Irkle, Iyemere, Jin, Kalra, Kapustin, Kevin Pappert, Kistowska, Krisenko, Laliberte, LaRocca, Lau, Li, Liu, Liu, Luga, Maldonado, Martin, Martin D. Bootman, Matthias Epple, Mfunyi, Migita, Mocsai, Molloy, Morgan, Nadra, Nakahara, Narayan, Ng, Pazar, Piccioli, Pugliese, Qu, Ragnauth, Ridker, Ruiz, Scimeca, Shamaa, Simon J. Cook, Smith, Song, Swaan, Vengrenyuk, Vigano, Virmani, Wang, Webber, Yana Dautova, Young   +76 more
core   +2 more sources

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Identification of Immunoreactive Tumour Antigens Using Free and Exosome-Associated Humoral Responses

Journal of Circulating Biomarkers, 2013
Altered tumour antigens can initiate cellular and humoral immune responses; however, they often fail to eliminate tumours. In humans, the presence of cancer is generally associated with the suppression of T cell activation and effector responses ...
Carolyn D. Roberson, Cicek Gercel-Taylor, Ying Qi, Kevin L. Schey, Douglas D. Taylor   +4 more
doaj   +1 more source

Comparative analysis of exosome isolation methods using culture supernatant for optimum yield, purity and downstream applications

Scientific Reports, 2019
Exosomes have received significant attention for their role in pathobiological processes and are being explored as a tool for disease diagnosis and management.
G. Patel, M. A. Khan, H. Zubair, S. Srivastava, Moh’d Khushman, Seema Singh, A. Singh   +6 more
semanticscholar   +1 more source

Exosome-derived noncoding RNAs in gastric cancer: functions and clinical applications

Molecular Cancer, 2021
Exosomes are a subpopulation of the tumour microenvironment (TME) that transmit various biological molecules to promote intercellular communication. Exosomes are derived from nearly all types of cells and exist in all body fluids. Noncoding RNAs (ncRNAs)
Xiaohuan Tang, Ting Guo, Xiangyu Gao, Xiaolong Wu, Xiaofang Xing, J. Ji, Ziyu Li   +6 more
semanticscholar   +1 more source

Roles of Exosomes and Exosomal MicroRNAs in Postoperative Sleep Disturbance

Nature and Science of Sleep, 2021
Postoperative sleep disturbance (PSD) often occurs in elderly patients after major surgery and exerts harmful effects on postoperative recovery. PSD may increase the incidence of postoperative fatigue, severe anxiety and depression, pain sensitivity, and cognitive dysfunction, which can cause or aggravate neurodegenerative diseases via amyloid ...
Junchao Zhu, Xiangyi Gu
openaire   +4 more sources

Genome-Wide Characterization of the RNA Exosome Complex in Relation to Growth, Development, and Pathogenicity of Fusarium graminearum

Microbiology Spectrum, 2023
The RNA exosome complex is a conserved, multisubunit RNase complex that contributes to the processing and degradation of RNAs in mammalian cells. However, the roles of the RNA exosome in phytopathogenic fungi and how it relates to fungal development and ...
Yanping Yuan, Xuzhao Mao, Yakubu Saddeeq Abubakar, Wenhui Zheng, Zonghua Wang, Jie Zhou, Huawei Zheng   +6 more
doaj   +1 more source

The role of extracellular vesicles in cutaneous remodeling and hair follicle dynamics [PDF]

, 2019
Extracellular vesicles (EVs), including exosomes, microvesicles, and apoptotic bodies, are cell-derived membranous structures that were originally catalogued as a way of releasing cellular waste products.
Carrasco, Elisa, Mittelbrunn, María, Soto-Heredero, Gonzalo   +2 more
core   +2 more sources

Exosome Theranostics: Biology and Translational Medicine

Theranostics, 2018
Exosomes are common membrane-bound nanovesicles that contain diverse biomolecules, such as lipids, proteins, and nucleic acids. Exosomes are derived from cells through exocytosis, are ingested by target cells, and can transfer biological signals between ...
Chuanjiang He, S. Zheng, Yan Luo, Ben Wang   +3 more
semanticscholar   +1 more source

Rewriting the dendritic cell code in cancer—from subset identity to immunotherapeutic design

FEBS Letters, EarlyView.
Dendritic cells (DCs) play central roles in cancer immunity but are often subverted by the tumor microenvironment. This review explores the diversity of DC subsets, their functional plasticity, and emerging therapeutic strategies to reprogram DCs for enhanced antitumor responses, including vaccines, in vivo targeting, and DC‐based immunotherapies ...
Estevão Carlos Silva Barcelos, Doriana Ricciuti, Giada Mondanelli, Marco Gargaro   +3 more
wiley   +1 more source