Exosome-based approaches in cancer along with unlocking new insights into regeneration of cancer-prone tissues [PDF]
Regen TherMost eukaryotic cells secrete extracellular vesicles called exosomes, which are involved in intercellular communication. Exosomes play a role in tumor development and metastasis by transporting bioactive chemicals from cancerous cells to other cells in ...
Safaei M +9 more
europepmc +1 more source
Microencapsulation technology by nature: Cell derived extracellular vesicles with therapeutic potential [PDF]
, 2013 Cell derived extracellular vesicles are submicron structures surrounded by phospholipid bilayer and released by both prokaryotic and eukaryotic cells.
Buzás, E., Falus, A., Kittel, Ágnes
core +1 more source
High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients. [PDF]
PLoS ONE, 2009 BACKGROUND: Metastatic melanoma is an untreatable cancer lacking reliable and non-invasive markers of disease progression. Exosomes are small vesicles secreted by normal as well as tumor cells.
Mariantonia Logozzi +17 more
doaj +1 more source
Isolation and characterization of exosomes for cancer research
Journal of Hematology & Oncology, 2020 Exosomes are a subset of extracellular vesicles that carry specific combinations of proteins, nucleic acids, metabolites, and lipids. Mounting evidence suggests that exosomes participate in intercellular communication and act as important molecular ...
Le Zhu +16 more
semanticscholar +1 more source
Cross talk between adipose tissue and placenta in obese and gestational diabetes mellitus pregnancies via exosomes [PDF]
, 2017 Obesity is an important public health issue worldwide, where it is commonly associated with the development of metabolic disorders, especially insulin resistance (IR).
Agustin Gutierrez, Jaime +11 more
core +2 more sources
Roles of exosomes in cardioprotection [PDF]
European Heart Journal, 2016 Exosomes are extracellular vesicles of endosomal origin which have emerged as key mediators of intercellular communication. All major cardiac cell types-including cardiomyocytes, endothelial cells, and fibroblasts-release exosomes that modulate cellular functions.
Barile Lucio +3 more
openaire +3 more sources
Emerging Role of Exosomes in the Joint Diseases
Cellular Physiology and Biochemistry, 2018 Exosomes are a subset of small, membrane-bound extracellular vesicles that are important for communication among cells. They originate from the cell membrane during endocytic internalization, and are stable in biological fluids, including blood and ...
Zeng Li +5 more
doaj +1 more source
Exosomes secreted by cortical neurons upon glutamatergic synapse activation specifically interact with neurons [PDF]
Journal of Extracellular Vesicles, 2014 Exosomes are nano-sized vesicles of endocytic origin released into the extracellular space upon fusion of multivesicular bodies with the plasma membrane. Exosomes represent a novel mechanism of cell–cell communication allowing direct transfer of proteins,
Mathilde Chivet +5 more
doaj +1 more source
The Potential of Exosomes in Allergy Immunotherapy
Vaccines, 2022 Allergic diseases represent a global health and economic burden of increasing significance. The lack of disease-modifying therapies besides specific allergen immunotherapy (AIT) which is not available for all types of allergies, necessitates the study of
Paul Engeroff, Monique Vogel
doaj +1 more source
Theranostics, 2019 Rationale: Chronic nonhealing diabetic wound therapy and complete skin regeneration remains a critical clinical challenge. The controlled release of bioactive factors from a multifunctional hydrogel was a promising strategy to repair chronic wounds ...
Chenggui Wang +8 more
semanticscholar +1 more source