Results 211 to 220 of about 177,584 (349)

Aptamer Engineering: Strategies for Discovering Functional Nucleic Acids for Next‐Generation Diagnostics and Biosensing

Advanced Science, EarlyView.
The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen, Ahlem Meziadi, Cyrill Brunner, Maureen McKeague, Lidija Malic, Maryam Tabrizian   +5 more
wiley   +1 more source

Exploring exosomal lncRNAs: unlocking the molecular code of tumor metastasis and drug resistance. [PDF]

Cancer Cell Int
Zhang R, Li M, Lu S, Wang A, Zhang S.
europepmc   +1 more source

Harnessing the power of exosomes for diagnosis, prognosis, and treatment of hematological malignancies [PDF]

Amirata Mohseni, Fatemeh Salehi, Samaneh Rostami, Kaveh Hadiloo, Mehrdad Hashemi, Zahra Baridjavadi, Fatemeh Ahangari, Nazli Karami, Fatemeh Samani, Safa Tahmasebi, Najma Farahani, Afshin Taheriazam   +11 more
openalex   +1 more source

Exosome-dependent Trafficking of HSP70 [PDF]

, 2005
Graeme I. Lancaster, Mark A. Febbraio
openalex   +1 more source

Crossing the Blood–Brain Barrier with Molecularly Imprinted Polymeric Nanocarriers: An Emerging Frontier in Brain Disease Therapy

Advanced Science, EarlyView.
Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley   +1 more source

One‐Step Coaxial 3D Printing of Pre‐Vascularized Skin Organoid Models with ADSC Microspheres for Enhanced Wound Healing

Advanced Science, EarlyView.
A multifunctional vascular bed platform is created using coaxial 3D printing, allowing the one‐step integration of organoid microspheres with perfusable vascular structures. This strategy enables rapid and functional vascularization of organoids to support tissue repair and vascularization, providing a scalable and translationally promising approach ...
Kunrui Wang, Xiang Lan, Jianwei Chen, Yu Wu, Delong Zhu, Xiangkai Kong, Ying Hu, Qian Liu, Kun Wang, Tao Xu, Lei Zhu   +10 more
wiley   +1 more source

Anti-Inflammatory and Skin-Lightening Activities of Exosomes Derived from <i>Latilactobacillus sakei</i> BK-5 Isolated from <i>Aster koraiensis</i> Flowers. [PDF]

J Microbiol Biotechnol
Lee CY, Choi BM, Kim DS, Choi H, Hong H, Chi WJ, Kim SY.   +6 more
europepmc   +1 more source

Exosome-Induced Regulation in Inflammatory Bowel Disease [PDF]

, 2019
Huiting Zhang, Liang Wang, Changyi Li, Yue Yu, Yanlin Yi, Jingyu Wang, Dapeng Chen   +6 more
openalex   +1 more source

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

Advanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang, Huijie Bian, Zhi‐Nan Chen   +2 more
wiley   +1 more source

Exosomal proteomics reveals fatty acid metabolism linked to gefitinib resistance in non-small cell lung cancer. [PDF]

Cell Biol Toxicol
Zhang Y, Zhu W, Zhu J, Hu R, Yang Y.
europepmc   +1 more source