Results 211 to 220 of about 222,944 (406)
Exosomes: A Novel Zika Virus Vaccine Candidate
, 2019 With the recent emergence of Zika virus (ZIKV) diseases, increasing global concern has driven the demand for a vaccine. One promising vaccine platform has presented itself in the form of exosomes: a subgroup of extracellular vesicles released by many ...
Furukawa, Carlos +1 more
core
Assessing Neuronal and Astrocyte Derived Exosomes From Individuals With Mild Traumatic Brain Injury for Markers of Neurodegeneration and Cytotoxic Activity. [PDF]
, 2019 Mild traumatic brain injury (mTBI) disproportionately affects military service members and is very difficult to diagnose. To-date, there is currently no blood-based, diagnostic biomarker for mTBI cases with persistent post concussive symptoms. To examine
Baker, Dewleen G +12 more
core
Opportunities in Therapeutic mRNA Stabilization: Sequence, Structure, Adjuvants and Vectors
Advanced Therapeutics, EarlyView.Current mRNA lipid nanoparticles rely on cold storage, which increases the cost and reduces access to the vaccines. As mRNA expands to other clinical opportunities, better methods to stabilize the medicines during shipping, storage, and delivery are needed.
Joshua A. Choe +4 more
wiley +1 more source
Modern Strategies in Wound Healing: The Rise of Bacterial Cellulose Dressings
Advanced Therapeutics, EarlyView.Bacterial cellulose (BC)‐based wound dressings combine high water retention, biocompatibility, and mechanical strength to support wound healing. This review highlights advanced functionalization strategies and fabrication techniques that enhance BC's therapeutic performance, establishing it as a promising material for next‐generation wound care ...
Elif Naz Gürsoy +4 more
wiley +1 more source
Pressure-dependent adhesion between solid-supported PC-lipid bilayers and vesicles under electric fields [PDF]
arXivFusion of lipid bilayers in membranes is important in processes from vesicle-cell interactions (as in drug delivery) to exosome-cell signaling, while transient transmembrane electric fields are known to occur spontaneously. Two contacting phosphatidylcholine (PC) lipid membranes are known to fuse into one under external electric fields, suggesting that
arxiv
The Biogenesis and Functions of Exosomes [PDF]
, 2002 Willem Stoorvogel +3 more
openalex +1 more source
Emerging Therapeutic Strategies for Hearing Loss
Advanced Therapeutics, EarlyView.Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han +9 more
wiley +1 more source
Strategy of a separation technique for different particles with the same size and zeta potential: Application of non-additive Asakura-Oosawa theory [PDF]
arXivIn this letter, we use knowledge gained from our recent study to present a technique for separation of nanoparticles such as exosomes, anticancer drugs, and vaccines. The technique involves adding non-adsorptive polymers to a system in which two types of nanoparticles with the same size and zeta potential are dispersed.
arxiv
Advanced Science, EarlyView.Exosome‐based nanoparticles (GC‐Exo‐CD16Ab) are designed to deliver glucocorticoids (GC) specifically to decidual CD16+ NK cells and macrophages. This targeted delivery effectively suppresses the cytotoxicity of decidual NK cells, inhibits M1 macrophage polarization, and modulates the decidual microenvironment.
Linlin Wang +17 more
wiley +1 more source