Results 61 to 70 of about 147,911 (307)

The Role of CDR1as in Proliferation and Differentiation of Human Umbilical Cord-Derived Mesenchymal Stem Cells

Stem Cells International, 2019
Mesenchymal stem cells derived from human umbilical cord (hucMSCs) are considered a promising tool for regenerative medicine. circRNAs as newly discovered noncoding RNAs are involved in multiple biological processes.
Lunyu Yang, Zhang Bin, Shi Hui, Li Rong, Benshuai You, Peipei Wu, Xinye Han, Hui Qian, Wenrong Xu   +8 more
doaj   +1 more source

Exosomes in lung cancer metastasis, diagnosis, and immunologically relevant advances

Frontiers in Immunology, 2023
Lung cancer is a chronic wasting disease with insidious onset and long treatment cycle. Exosomes are specialized extracellular vesicles, at first exosomes were considered as a transporter of cellular metabolic wastes, but recently many studies have ...
Jianhua Zhao, Xiwen Li, Lele Liu, Zhen Zhu, Chunyan He   +4 more
doaj   +1 more source

Adipose-Derived Stem Cell Exosomes Alleviate Psoriasis Serum Exosomes-Induced Inflammation by Regulating Autophagy and Redox Status in Keratinocytes

, 2023
Hye Ran Kim,1 So Yeon Lee,1 Ga Eun You,2 Hye One Kim,1 Chun Wook Park,1 Bo Young Chung1 1Department of Dermatology, Hallym University Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, 07441, Korea; 2Research and Development ...
Lee SY, Chung BY, Park CW, Kim HO, Kim HR, You GE   +5 more
core  

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Three-Dimensional Hepatocyte Spheroids: Model for Assessing Chemotherapy in Hepatocellular Carcinoma

Biomedicines
Background: Three-dimensional cellular models provide a more comprehensive representation of in vivo cell properties, encompassing physiological characteristics and drug susceptibility.
Felix Royo, Clara Garcia-Vallicrosa, Maria Azparren-Angulo, Guillermo Bordanaba-Florit, Silvia Lopez-Sarrio, Juan Manuel Falcon-Perez   +5 more
doaj   +1 more source

The role of mesenchymal stem cells derived exosomes as a novel nanobiotechnology target in the diagnosis and treatment of cancer

Frontiers in Bioengineering and Biotechnology, 2023
Mesenchymal stem cells (MSCs), one of the most common types of stem cells, are involved in the modulation of the tumor microenvironment (TME). With the advancement of nanotechnology, exosomes, especially exosomes secreted by MSCs, have been found to play
You Zhou, Yuqing Dong, Aixue Zhang, Jibin Wu, Qiang Sun   +4 more
doaj   +1 more source

Exosomes and exosomal miRNAs in cardiovascular protection and repair [PDF]

Vascular Pharmacology, 2015
Cell-cell communication between cardiac and vascular cells and from stem and progenitor cells to differentiated cardiovascular cells is both an important and complex process, achieved through a diversity of mechanisms that have an impact on cardiovascular biology, disease and therapeutics.
Emanueli, Costanza, Shearn, Andrew I U, Angelini, Gianni D, Sahoo, Susmita   +3 more
openaire   +3 more sources

Isolation and Detection of Exosomes Using Fe2O3 Nanoparticles

, 2021
Magnetic nanozymes with peroxidase-mimicking activity have been widely investigated for developing molecular biosensors. Herein, we report a starch-assisted method for the synthesis of a novel class of carboxyl group-functionalized iron oxide ...
Umer, M, Mahboobeh Shahbazi, Saeed, A, Muhammad Umer, Kostya Ostrikov, Aiden Jabur, Farhana, FZ, Shiddiky, MJA, Ayad Saeed, Sonar, P, Fatema Zerin Farhana, Hyun Jae Nam, Firoz, SH, Nam, HJ, Pannu, AS, Jabur, A, Muhammad J. A. Shiddiky, Prashant Sonar, Amandeep Singh Pannu, Shahbazi, M, Ostrikov, K, Shakhawat H. Firoz   +21 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

The RNA exosome and RNA exosome-linked disease [PDF]

RNA, 2017
The RNA exosome is an evolutionarily conserved, ribonuclease complex that is critical for both processing and degradation of a variety of RNAs. Cofactors that associate with the RNA exosome likely dictate substrate specificity for this complex. Recently, mutations in genes encoding both structural subunits of the RNA exosome and its cofactors have been
Derrick J. Morton, Emily G. Kuiper, Stephanie K. Jones, Sara W. Leung, Anita H. Corbett, Milo B. Fasken   +5 more
openaire   +2 more sources