Results 41 to 50 of about 115,777 (264)
Glioblastoma-Derived Exosomes as Nanopharmaceutics for Improved Glioma Treatment
Pharmaceutics, 2022 The use of cancer-derived exosomes has been studied in several cancer types, but the cancer-targeting efficacy of glioma-derived exosomes has not been investigated in depth for malignant glioblastoma (GBM) cells. In this study, exosomes were derived from
Hyeji Lee +7 more
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Cells, 2020 Research on extracellular vesicles (EVs) is growing exponentially due to an increasing appreciation of EVs as disease biomarkers and therapeutics, an expanding number of EV-containing materials under study, and application of new preparation, detection ...
Felix Royo +4 more
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Exosomes in lung cancer metastasis, diagnosis, and immunologically relevant advances
Frontiers in Immunology, 2023 Lung cancer is a chronic wasting disease with insidious onset and long treatment cycle. Exosomes are specialized extracellular vesicles, at first exosomes were considered as a transporter of cellular metabolic wastes, but recently many studies have ...
Jianhua Zhao +4 more
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Exosomes and exosomal miRNAs in cardiovascular protection and repair [PDF]
Vascular Pharmacology, 2015 Cell-cell communication between cardiac and vascular cells and from stem and progenitor cells to differentiated cardiovascular cells is both an important and complex process, achieved through a diversity of mechanisms that have an impact on cardiovascular biology, disease and therapeutics.
Emanueli, Costanza +3 more
openaire +3 more sources
Assessment of bovine milk exosome preparation and lyophilized powder stability
Journal of Extracellular BiologyExosomes are cell‐derived nanovesicles that play a crucial role in intercellular communication, presenting promising potential as biomarkers and therapeutic agents.
Lu Lu +12 more
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Tumour exosomes display differential mechanical and complement activation properties dependent on malignant state: implications in endothelial leakiness [PDF]
Journal of Extracellular Vesicles, 2015 Background: Exosomes have been implicated in tumour progression and metastatic spread. Little is known of the effect of mechanical and innate immune interactions of malignant cell-derived exosomes on endothelial integrity, which may relate to increased ...
Bradley Whitehead +8 more
doaj +1 more source
Sensors, 2022 Dielectrophoresis (DEP) refers to a type of electrical motion of dielectric particles. Because DEP is caused by particle polarization, it has been utilized to characterize particles.
Hao Chen +4 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
The RNA exosome and RNA exosome-linked disease [PDF]
RNA, 2017 The RNA exosome is an evolutionarily conserved, ribonuclease complex that is critical for both processing and degradation of a variety of RNAs. Cofactors that associate with the RNA exosome likely dictate substrate specificity for this complex. Recently, mutations in genes encoding both structural subunits of the RNA exosome and its cofactors have been
Derrick J. Morton +5 more
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source