Results 41 to 50 of about 176,486 (297)

Methods for Separation and Characterization of Extracellular Vesicles: Results of a Worldwide Survey Performed by the ISEV Rigor and Standardization Subcommittee

open access: yesCells, 2020
Research on extracellular vesicles (EVs) is growing exponentially due to an increasing appreciation of EVs as disease biomarkers and therapeutics, an expanding number of EV-containing materials under study, and application of new preparation, detection ...
Felix Royo   +4 more
doaj   +1 more source

Glioblastoma-Derived Exosomes as Nanopharmaceutics for Improved Glioma Treatment

open access: yesPharmaceutics, 2022
The use of cancer-derived exosomes has been studied in several cancer types, but the cancer-targeting efficacy of glioma-derived exosomes has not been investigated in depth for malignant glioblastoma (GBM) cells. In this study, exosomes were derived from
Hyeji Lee   +7 more
doaj   +1 more source

Tumour exosomes display differential mechanical and complement activation properties dependent on malignant state: implications in endothelial leakiness [PDF]

open access: yesJournal of Extracellular Vesicles, 2015
Background: Exosomes have been implicated in tumour progression and metastatic spread. Little is known of the effect of mechanical and innate immune interactions of malignant cell-derived exosomes on endothelial integrity, which may relate to increased ...
Bradley Whitehead   +8 more
doaj   +1 more source

Characterization of Extra-Cellular Vesicle Dielectrophoresis and Estimation of Its Electric Properties

open access: yesSensors, 2022
Dielectrophoresis (DEP) refers to a type of electrical motion of dielectric particles. Because DEP is caused by particle polarization, it has been utilized to characterize particles.
Hao Chen   +4 more
doaj   +1 more source

Exosome Manufacturing Status [PDF]

open access: yesFuture Medicinal Chemistry, 2019
Exosomes are secreted by mammalian cells and are widely distributed in cellular systems. They are a medium of information and material transmission. The complexity of exosome nature and function is not thoroughly understood. Nevertheless, they are being confirmed as mediators of intercellular communication and play significant roles in many ...
William, Whitford, Peter, Guterstam
openaire   +2 more sources

Assessment of bovine milk exosome preparation and lyophilized powder stability

open access: yesJournal of Extracellular Biology
Exosomes are cell‐derived nanovesicles that play a crucial role in intercellular communication, presenting promising potential as biomarkers and therapeutic agents.
Lu Lu   +12 more
doaj   +1 more source

The role of mesenchymal stem cells derived exosomes as a novel nanobiotechnology target in the diagnosis and treatment of cancer

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
Mesenchymal stem cells (MSCs), one of the most common types of stem cells, are involved in the modulation of the tumor microenvironment (TME). With the advancement of nanotechnology, exosomes, especially exosomes secreted by MSCs, have been found to play
You Zhou   +4 more
doaj   +1 more source

Targeted-pig trial on safety and immunogenicity of serum-derived extracellular vesicles enriched fractions obtained from Porcine Respiratory and Reproductive virus infections [PDF]

open access: yes, 2018
The Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) is the etiological agent of one of the most important swine diseases with a significant economic burden worldwide.
Borrás, Francesc E.   +6 more
core   +4 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Exosomes regulate neurogenesis and circuit assembly. [PDF]

open access: yes, 2019
Exosomes are thought to be released by all cells in the body and to be involved in intercellular communication. We tested whether neural exosomes can regulate the development of neural circuits.
Carromeu, Cassiano   +7 more
core  

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