Results 41 to 50 of about 147,911 (307)

Assessing the role of surface glycans of extracellular vesicles on cellular uptake

open access: yesScientific Reports, 2019
Extracellular vesicles (EVs) are important mediators of cell-cell communication in a broad variety of physiological contexts. However, there is ambiguity around the fundamental mechanisms by which these effects are transduced, particularly in relation to
Charles Williams   +8 more
doaj   +1 more source

Extracellular vesicles released by steatotic hepatocytes alter adipocyte metabolism

open access: yesJournal of Extracellular Biology, 2022
The composition of extracellular vesicles (EVs) is altered in many pathological conditions, and their molecular content provides essential information on features of parent cells and mechanisms of crosstalk between cells and organs.
J.E. Mleczko   +16 more
doaj   +1 more source

Finding the Exosome [PDF]

open access: yes, 2010
We describe the events surrounding the identification of the exosome complex and the subsequent early development of the field. Like many scientific discoveries, the initial identification and characterization ofthe exosome was based on a combination of skill, good fortune--and the availability of cutting edge technology.
Mitchell, Phil, Tollervey, David
openaire   +4 more sources

Quantification of Exosomes [PDF]

open access: yesJournal of Cellular Physiology, 2017
Exosomes are released by cells as self‐contained vesicles with an intact lipid bilayer that encapsulates a small portion of the parent cell. Exosomes have been studied widely as information‐rich sources of potential biomarkers that can reveal cellular physiology.
Erik H, Koritzinsky   +3 more
openaire   +2 more sources

Exosomes derived from synovial fibroblasts from patients with rheumatoid arthritis promote macrophage migration that can be suppressed by miR-124-3p

open access: yesHeliyon, 2023
Objectives: Exosomes are potent vehicles for intercellular communication. Rheumatoid arthritis (RA) is a chronic systemic disease of unknown etiology. Local administration of miR-124 precursor to rats with adjuvant-induced arthritis suppresses systemic ...
Yuji Nakamachi   +7 more
doaj   +1 more source

The Potential of Exosomes in Allergy Immunotherapy [PDF]

open access: yes, 2022
Allergic diseases represent a global health and economic burden of increasing significance. The lack of disease-modifying therapies besides specific allergen immunotherapy (AIT) which is not available for all types of allergies, necessitates the study of
Vogel, Monique   +3 more
core   +2 more sources

Artificial exosomes for translational nanomedicine

open access: yesJournal of Nanobiotechnology, 2021
Exosomes are lipid bilayer membrane vesicles and are emerging as competent nanocarriers for drug delivery. The clinical translation of exosomes faces many challenges such as massive production, standard isolation, drug loading, stability and quality ...
Yong-Jiang Li   +7 more
doaj   +1 more source

Exosomes and miRNAs in disease pathogenesis and opportunities for molecular targeting [PDF]

open access: yes, 2016
Exosomes/extracellular vesicles (EVs) are cell-derived mixed-populations of vesicles released by almost all cells into the intercellular microenvironment, ending up in the circulation.
Momen Heravi, F.
core   +1 more source

Exosome-drug conjugates delivery: a promising strategy for ameliorating the pharmacokinetic profile of artesunate

open access: yesFrontiers in Bioengineering and Biotechnology
Artesunate (ATS) is considered the most widely employed artemisnin derivative in the treatment of Plasmodium falciparum malaria. However, poor solubility and low bioavailability of ATS limit its further clinical application.
Da Wang   +12 more
doaj   +1 more source

Cell Infectivity in relation to bovine leukemia virus gp51 and p24 in bovine milk exosomes. [PDF]

open access: yesPLoS ONE, 2013
Exosomes are small membranous microvesicles (40-100 nm in diameter) and are extracellularly released from a wide variety of cells. Exosomes contain microRNA, mRNA, and cellular proteins, which are delivered into recipient cells via these exosomes, and ...
Tetsuya Yamada   +3 more
doaj   +1 more source

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