Results 41 to 50 of about 13,468 (215)
Glioblastoma-Derived Exosomes as Nanopharmaceutics for Improved Glioma Treatment
Pharmaceutics, 2022 The use of cancer-derived exosomes has been studied in several cancer types, but the cancer-targeting efficacy of glioma-derived exosomes has not been investigated in depth for malignant glioblastoma (GBM) cells. In this study, exosomes were derived from
Hyeji Lee +7 more
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Exosomes in lung cancer metastasis, diagnosis, and immunologically relevant advances
Frontiers in Immunology, 2023 Lung cancer is a chronic wasting disease with insidious onset and long treatment cycle. Exosomes are specialized extracellular vesicles, at first exosomes were considered as a transporter of cellular metabolic wastes, but recently many studies have ...
Jianhua Zhao +4 more
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Science, 2008 Two pathways within endosomes use specific protein complexes or membrane domains to direct cargo for degradation or secretion from cells.
Marsh, M., van Meer, G.
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Assessment of bovine milk exosome preparation and lyophilized powder stability
Journal of Extracellular BiologyExosomes are cell‐derived nanovesicles that play a crucial role in intercellular communication, presenting promising potential as biomarkers and therapeutic agents.
Lu Lu +12 more
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Sensors, 2022 Dielectrophoresis (DEP) refers to a type of electrical motion of dielectric particles. Because DEP is caused by particle polarization, it has been utilized to characterize particles.
Hao Chen +4 more
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, 2010 We describe the events surrounding the identification of the exosome complex and the subsequent early development of the field. Like many scientific discoveries, the initial identification and characterization ofthe exosome was based on a combination of skill, good fortune--and the availability of cutting edge technology.
Mitchell, Phil, Tollervey, David
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
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Exosomes and exosomal miRNAs in cardiovascular protection and repair [PDF]
Vascular Pharmacology, 2015 Cell-cell communication between cardiac and vascular cells and from stem and progenitor cells to differentiated cardiovascular cells is both an important and complex process, achieved through a diversity of mechanisms that have an impact on cardiovascular biology, disease and therapeutics.
Emanueli, Costanza +3 more
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Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
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Stem Cells International, 2019 Mesenchymal stem cells derived from human umbilical cord (hucMSCs) are considered a promising tool for regenerative medicine. circRNAs as newly discovered noncoding RNAs are involved in multiple biological processes.
Lunyu Yang +8 more
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