Results 31 to 40 of about 13,468 (215)
Role of Exosomes and Exosomal microRNAs in Cancer
Future Science OA, 2020 A growing body of evidence indicates that exosomes play a critical role in the cell-cell communication process. Exosomes are biological nanoparticles with an average diameter of 30-100 nm in size and are produced by almost all cell types in the human body; however, cancer cells contain higher concentrations of exosomes than healthy cells.
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Assessing the role of surface glycans of extracellular vesicles on cellular uptake
Scientific Reports, 2019 Extracellular vesicles (EVs) are important mediators of cell-cell communication in a broad variety of physiological contexts. However, there is ambiguity around the fundamental mechanisms by which these effects are transduced, particularly in relation to
Charles Williams +8 more
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Heliyon, 2023 Objectives: Exosomes are potent vehicles for intercellular communication. Rheumatoid arthritis (RA) is a chronic systemic disease of unknown etiology. Local administration of miR-124 precursor to rats with adjuvant-induced arthritis suppresses systemic ...
Yuji Nakamachi +7 more
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Quantification of Exosomes [PDF]
Journal of Cellular Physiology, 2017 Exosomes are released by cells as self‐contained vesicles with an intact lipid bilayer that encapsulates a small portion of the parent cell. Exosomes have been studied widely as information‐rich sources of potential biomarkers that can reveal cellular physiology.
Erik H, Koritzinsky +3 more
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Artificial exosomes for translational nanomedicine
Journal of Nanobiotechnology, 2021 Exosomes are lipid bilayer membrane vesicles and are emerging as competent nanocarriers for drug delivery. The clinical translation of exosomes faces many challenges such as massive production, standard isolation, drug loading, stability and quality ...
Yong-Jiang Li +7 more
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Cell Infectivity in relation to bovine leukemia virus gp51 and p24 in bovine milk exosomes. [PDF]
PLoS ONE, 2013 Exosomes are small membranous microvesicles (40-100 nm in diameter) and are extracellularly released from a wide variety of cells. Exosomes contain microRNA, mRNA, and cellular proteins, which are delivered into recipient cells via these exosomes, and ...
Tetsuya Yamada +3 more
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Exosomes: Diagnostic and Therapeutic Implications in Cancer
Pharmaceutics, 2023 Exosomes are a subset of extracellular vesicles produced by all cells, and they are present in various body fluids. Exosomes play crucial roles in tumor initiation/progression, immune suppression, immune surveillance, metabolic reprogramming ...
Hyein Jo, Kyeonghee Shim, Dooil Jeoung
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Frontiers in Bioengineering and BiotechnologyArtesunate (ATS) is considered the most widely employed artemisnin derivative in the treatment of Plasmodium falciparum malaria. However, poor solubility and low bioavailability of ATS limit its further clinical application.
Da Wang +12 more
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Cells, 2020 Research on extracellular vesicles (EVs) is growing exponentially due to an increasing appreciation of EVs as disease biomarkers and therapeutics, an expanding number of EV-containing materials under study, and application of new preparation, detection ...
Felix Royo +4 more
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Tumour exosomes display differential mechanical and complement activation properties dependent on malignant state: implications in endothelial leakiness [PDF]
Journal of Extracellular Vesicles, 2015 Background: Exosomes have been implicated in tumour progression and metastatic spread. Little is known of the effect of mechanical and innate immune interactions of malignant cell-derived exosomes on endothelial integrity, which may relate to increased ...
Bradley Whitehead +8 more
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