Results 31 to 40 of about 176,486 (297)

Exosomes derived from synovial fibroblasts from patients with rheumatoid arthritis promote macrophage migration that can be suppressed by miR-124-3p

open access: yesHeliyon, 2023
Objectives: Exosomes are potent vehicles for intercellular communication. Rheumatoid arthritis (RA) is a chronic systemic disease of unknown etiology. Local administration of miR-124 precursor to rats with adjuvant-induced arthritis suppresses systemic ...
Yuji Nakamachi   +7 more
doaj   +1 more source

Microvesicles and exosomes: new players in metabolic and cardiovascular disease [PDF]

open access: yes, 2016
The past decade has witnessed an exponential increase in the number of publications referring to extracellular vesicles (EVs). For many years considered to be extracellular debris, EVs are now seen as novel mediators of endocrine signalling via cell-to ...
Charlotte Lawson   +21 more
core   +2 more sources

Artificial exosomes for translational nanomedicine

open access: yesJournal of Nanobiotechnology, 2021
Exosomes are lipid bilayer membrane vesicles and are emerging as competent nanocarriers for drug delivery. The clinical translation of exosomes faces many challenges such as massive production, standard isolation, drug loading, stability and quality ...
Yong-Jiang Li   +7 more
doaj   +1 more source

A new landscape of host–protozoa interactions involving the extracellular vesicles world [PDF]

open access: yes, 2018
This version is free to view and download for private research and study only. Not for re-distribution, re-sale or use in derivative works. © Cambridge University Press 2018Extracellular vesicles (EVs) are released by a wide number of cells including ...
Bruno Gavinho   +11 more
core   +2 more sources

Cell Infectivity in relation to bovine leukemia virus gp51 and p24 in bovine milk exosomes. [PDF]

open access: yesPLoS ONE, 2013
Exosomes are small membranous microvesicles (40-100 nm in diameter) and are extracellularly released from a wide variety of cells. Exosomes contain microRNA, mRNA, and cellular proteins, which are delivered into recipient cells via these exosomes, and ...
Tetsuya Yamada   +3 more
doaj   +1 more source

Exosomes: Diagnostic and Therapeutic Implications in Cancer

open access: yesPharmaceutics, 2023
Exosomes are a subset of extracellular vesicles produced by all cells, and they are present in various body fluids. Exosomes play crucial roles in tumor initiation/progression, immune suppression, immune surveillance, metabolic reprogramming ...
Hyein Jo, Kyeonghee Shim, Dooil Jeoung
doaj   +1 more source

Profiling of RNAs from Human Islet-Derived Exosomes in a Model of Type 1 Diabetes [PDF]

open access: yes, 2019
Type 1 diabetes (T1D) is characterized by the immune-mediated destruction of insulin-producing islet β cells. Biomarkers capable of identifying T1D risk and dissecting disease-related heterogeneity represent an unmet clinical need.
Evans-Molina, Carmella   +4 more
core   +2 more sources

Exosomes in lung cancer metastasis, diagnosis, and immunologically relevant advances

open access: yesFrontiers in Immunology, 2023
Lung cancer is a chronic wasting disease with insidious onset and long treatment cycle. Exosomes are specialized extracellular vesicles, at first exosomes were considered as a transporter of cellular metabolic wastes, but recently many studies have ...
Jianhua Zhao   +4 more
doaj   +1 more source

Proteomic and epigenomic markers of sepsis-induced delirium (SID) [PDF]

open access: yes, 2015
In elderly population sepsis is one of the leading causes of intensive care unit (ICU) admissions in the United States. Sepsis-induced delirium (SID) is the most frequent cause of delirium in ICU (Martin et al., 2010). Together delirium and SID represent
Adonis eSfera   +5 more
core   +2 more sources

Exosome-drug conjugates delivery: a promising strategy for ameliorating the pharmacokinetic profile of artesunate

open access: yesFrontiers in Bioengineering and Biotechnology
Artesunate (ATS) is considered the most widely employed artemisnin derivative in the treatment of Plasmodium falciparum malaria. However, poor solubility and low bioavailability of ATS limit its further clinical application.
Da Wang   +12 more
doaj   +1 more source

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