Results 11 to 20 of about 176,486 (297)
Exosomes and Exosomal miRNA in Respiratory Diseases [PDF]
Mediators of Inflammation, 2016 Exosomes are nanosized vesicles released from every cell in the body including those in the respiratory tract and lungs. They are found in most body fluids and contain a number of different biomolecules including proteins, lipids, and both mRNA and ...
Adcock, IM +5 more
core +11 more sources
Circulation Research, 2015 Nature has designed clever ways for information and material transfer between cells and for intercellular coordination. Mechanisms include direct cell contact, gap junctions, and receptor-ligand signaling. In the past decade, a particular form of exchange has gained increasing attention, and that is intercellular transfer of extracellular vesicles ...
Yin, Tintut, Linda L, Demer
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The Scientific World JOURNAL, 2009 Exosomes are nanovesicles of endocytic origin that are secreted into the extracellular space or body fluids when a multivesicular body (MVB) fuses with the cell membrane. Interest in exosomes intensified after their description in antigen-presenting cells and the observation that they can significantly moderate immune responsesin vivo.
Irena Dimov +2 more
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EMBnet.journal, 2020 Extracellular vesicles have been the focus of a large number of studies in the past five years. Exosomes, a subgroup of extracellular vesicles, are of particularly high interest because they partake in a wide number of biological pathways. Produced by a variety of cells, exosomes have an important role in both physiological and pathological conditions.
Mitsis, Thanasis +6 more
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Exosomes released from breast cancer carcinomas stimulate cell movement [PDF]
, 2015 For metastasis to occur cells must communicate with to their local environment to initiate growth and invasion. Exosomes have emerged as an important mediator of cell-to-cell signalling through the transfer of molecules such as mRNAs, microRNAs, and ...
Gucek, Marjan +5 more
core +9 more sources
Therapeutic Advances of Stem Cell-Derived Extracellular Vesicles in Regenerative Medicine
Cells, 2020 Extracellular vesicles (EVs), which are the main paracrine components of stem cells, mimic the regenerative capacity of these cells. Stem cell-derived EVs (SC-EVs) have been used for the treatment of various forms of tissue injury in preclinical trials ...
Lei Yin +8 more
doaj +1 more source
Cells, 2021 Cancer multidrug resistance (MDR) is one of the main challenges for cancer treatment efficacy. MDR is a phenomenon by which tumor cells become resistant to several unrelated drugs.
Diana Sousa +7 more
doaj +1 more source
Future Science OA, 2021 Exosomes are a new horizon in modern therapy, presenting exciting new opportunities for advanced drug delivery and targeted release. Exosomes are small extracellular vesicles with a size range of 30-100 nm, secreted by all cell types in the human body and carrying a unique collection of DNA fragments, RNA species, lipids, protein biomarkers ...
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Digital detection of exosomes by interferometric imaging [PDF]
, 2016 Exosomes, which are membranous nanovesicles, are actively released by cells and have been attributed to roles in cell-cell communication, cancer metastasis, and early disease diagnostics.
Benussi, Luisa +13 more
core +8 more sources
Annual Review of Biochemistry, 2019 Exosomes are small, single-membrane, secreted organelles of ∼30 to ∼200 nm in diameter that have the same topology as the cell and are enriched in selected proteins, lipids, nucleic acids, and glycoconjugates. Exosomes contain an array of membrane-associated, high-order oligomeric protein complexes, display pronounced molecular heterogeneity, and are ...
Pegtel, D. Michiel, Gould, Stephen J.
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