Results 121 to 130 of about 11,626 (172)

Staphylococcal exotoxin activation of T cells. Role of exotoxin-MHC class II binding affinity and class II isotype

The Journal of Immunology, 1991
Abstract Staphylococcal enterotoxins (SE) and toxic shock syndrome toxin-1 bind directly to class II molecules of the MHC and stimulate T cells based predominantly on the V beta segment used by the TCR. We investigated the relationship between the class II binding affinities of four of these exotoxins, SEA, SEB, SEC1, and toxic shock ...
J A, Mollick   +3 more
openaire   +2 more sources

Biological effects of Pseudomonas aeruginosa exotoxin A: Lymphoproliferation of T lymphocytes in athymic mice

European Journal of Epidemiology, 1988
Pseudomonas aeruginosa exotoxin A has been observed to exert modulatory effects on the immune response. The present study examines the ability of exotoxin A to induce proliferation of splenocytes from athymic nu/nu mice. We observed that exotoxin A induced the proliferation of athymic nude splenocytes which could be abrogated by heating the toxin at 70
P S, Holt, M L, Misfeldt
openaire   +2 more sources

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