Results 61 to 70 of about 19,438 (226)

Aspergillus fumigatus enhances elastase production in pseudomonas aeruginosaco-cultures [PDF]

, 2015
In the cystic fibrosis (CF) lung the presence of bacteria and fungi in the airways promotes an inflammatory response causing progressive lung damage, ultimately leading to high rates of morbidity and mortality.
Kerr, Stephen, Lappin, David F., Mackay, William G., Rajendran, Ranjith, Ramage, Gordon, Smith, Karen, Williams, Craig   +6 more
core   +1 more source

Streptococcus pyogenes pharyngitis: characterization of strains by multilocus enzyme genotype, M and T protein serotype, and pyrogenic exotoxin gene probing [PDF]

Journal of Clinical Microbiology, 1992
Multilocus enzyme electrophoresis, serological characterization of M and T proteins, and probing for pyrogenic exotoxin A and C genes were used to investigate the bacteriologic epidemiology of strains of Streptococcus pyogenes recovered primarily from patients with recurrent pharyngitis.
J M, Musser, B M, Gray, P M, Schlievert, M E, Pichichero   +3 more
openaire   +2 more sources

The future of antiviral immunotoxins [PDF]

, 2016
There is a constant need for new therapeutic interventions in a wide range of infectious diseases. Over the past few years, the immunotoxins have entered the stage as promising antiviral treatments.
Høy Jakobsen, Mette, Kledal, Thomas N, Rosenkilde, Mette M., Spiess, K.   +3 more
core   +1 more source

Attenuated Bacteria‐Based Tumor Therapy: Clinical Application Risks, Marketing Approval Restrictions, and Coping Strategies

Advanced Science, Volume 13, Issue 16, 18 March 2026.
This review comprehensively overviews attenuated bacteria‐based tumor therapy, highlighting key methodologies and recent progress. It examines strategies for enhancing safety, stabilizing efficacy, optimizing manufacturing, and navigating regulatory pathways.
Yucheng Liu, Junhong Yao, Jiaxin Deng, Minjie Zhou, Kaiyue Shen, Shishuo Sun, Xiaoge Gao, Qing Zhang, Haiheng Xu   +8 more
wiley   +1 more source

Targeting Group A Streptococcus with a Recombinant Chimeric Vaccine: Integrating ScpA and SpeA Fragments

Медицинская иммунология
Our objective was to develop a vaccine against group A streptococci (Streptococcus pyogenes, GAS), the causative agent of a broad spectrum of infections with varying severity.
N. V. Duplik, G. F. Leontieva, T. A. Kramskaya, K. P. Bogatireva, T. V. Gupalova, E. A. Bormotova, I. V. Koroleva, A. N. Suvorov   +7 more
doaj   +1 more source

A Galactose-Binding Lectin Isolated from Aplysia kurodai (Sea Hare) Eggs Inhibits Streptolysin-Induced Hemolysis

Molecules, 2014
A specific galactose-binding lectin was shown to inhibit the hemolytic effect of streptolysin O (SLO), an exotoxin produced by Streptococcus pyogenes.
Imtiaj Hasan, Miharu Watanabe, Naoto Ishizaki, Yoshiko Sugita-Konishi, Yasushi Kawakami, Jun Suzuki, Chikaku Dogasaki, Sultana Rajia, Sarkar M. A. Kawsar, Yasuhiro Koide, Robert A. Kanaly, Shigeki Sugawara, Masahiro Hosono, Yukiko Ogawa, Yuki Fujii, Hideyuki Iriko, Jiharu Hamako, Taei Matsui, Yasuhiro Ozeki   +18 more
doaj   +1 more source

Detection of Fungal Translocation in Patients With Alcohol Use Disorder Using a Real‐Time PCR Assay

APMIS, Volume 134, Issue 3, March 2026.
ABSTRACT Gut microbiota plays a key role in triggering various diseases. However, translocation studies focus on bacteria, neglecting fungal elements, while fungi seem also involved in triggering various diseases. Aim of this study was to assess whether fungal elements were able to translocate in patients with AUD (alcohol use disorder) and to verify ...
Nathalie Pansu, Pascal Drakulovski, Donika Krasteva, Virginie Bellet, Jean‐Philippe Lavigne, Catherine Dunyach‐Remy, Florian Salipante, Alex Yahiaoui‐Martinez, Hélène Donnadieu‐Rigole, Sébastien Bertout   +9 more
wiley   +1 more source

Imipenem Resistance Mediated by bla_OXA-913 Gene in Pseudomonas aeruginosa

Antibiotics, 2021
Treatment of infectious diseases caused by carbapenem-resistant Pseudomonas aeruginosa is becoming a greater challenge. This study aimed to identify the imipenem resistance mechanism in P. aeruginosa isolated from a dog. Minimum Inhibitory Concentration (
Dong-Chan Moon, Abraham Fikru Mechesso, Hee-Young Kang, Su-Jeong Kim, Ji-Hyun Choi, Hyun-Ju Song, Soon-Seek Yoon, Suk-Kyung Lim   +7 more
doaj   +1 more source

Exploring the genetics of irritable bowel syndrome: A GWA study in the general population and replication in multinational case-control cohorts [PDF]

, 2014
OBJECTIVE: IBS shows genetic predisposition, but adequately powered gene-hunting efforts have been scarce so far. We sought to identify true IBS genetic risk factors by means of genome-wide association (GWA) and independent replication studies.
Agreus, Lars, Andreasson, Anna, Assadi, Ghazaleh, Barbara, Giovanni, Barbaro, Raffaella, Bellini, Massimo, Blandizzi, Corrado, Boeckxstaens, Guy, Bresso, Francesca, Burwinkel, Barbara, Camilleri, Michael, Colucci, Rocchina Lucia, D'Amato, Mauro, Daly, Mark J., Dlugosz, Aldona, Ek, Weronica E., Gambaccini, Dario, Gazouli, Maria, Holliday, Elizabeth G., Houghton, Lesley, Karamanolis, George, Karling, Pontus, Li, Ling, Lindberg, Greger, Magnusson, Patrik, Marchi, Santino, Niesler, Beate, Ohlsson, Bodil, Papadaki, Evangelia, Pedersen, Nancy L., Rafter, Joseph, Rappold, Gudrun, Reznichenko, Anna, Ripke, Stephan, Rivera, Natalia V., Schmidt, Peter T., Simren, Magnus, Stanghellini, Vincenzo, Surowy, Harald, Talley, Nicholas J., Tornblom, Hans, Walter, Susanna, Wouters, Mira M., Zucchelli, Marco   +43 more
core   +1 more source

Equine botulism

Equine Veterinary Journal, Volume 58, Issue 2, Page 333-347, March 2026.
Abstract Botulism is a severe and often fatal disease in equine patients worldwide. Clostridium botulinum is a ubiquitous soil organism which produces a potent neurotoxin resulting in neuromuscular blockade and flaccid paralysis in affected animals. Definitive diagnosis is often impractical or impossible, leading to diagnosis and treatment based on ...
Kali Slavik, Robert Whitlock, Amy Johnson   +2 more
wiley   +1 more source