Results 101 to 110 of about 3,439,839 (252)

Erreur et vérité de l’enfance selon Malebranche : quelle pédagogie malebranchienne ?

Cahiers François Viète
We know Nicolas Malebranche’s warning against the dangers of childhood. What is overlooked, on the other hand, quite often is the singular fact that the First part of the second Book of the Recherche de la vérité devoted to the errors of the imagination ...
Vincent Geny
doaj   +1 more source

Labor supply dynamics, unemployment and experience in the labor market [PDF]

In the last decades, OECD labor markets faced important labor supply changes with the arrival of women and the cohorts of the baby-boom. Using a survey where workers declare their true employment experience, this paper argues that these supply trends ...
Etienne WASMER
core  

Une expérience d'encadrement départemental en français [PDF]

, 2011
Depuis l’automne 2008, le Département de français du Cégep André-Laurendeau a mis en place des « mesures d’encadrement et de suivi des étudiants » qui permettent par différents moyens aux étudiants inscrits aux trois premiers cours de français de réussir
Poulin, Marie-Pier, Roberge, Julie, Roger, Jean-Paul   +2 more
core  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Contribution de la caisse de solidarité interscolaire pour l’intégration effective de l’approche par compétence : expérience et attente des acteurs de la ville de Kikwit, Province du Kwilu, RD Congo

Revue Congolaise des Sciences et Technologies
A Kikwit l'approche par compétences est théoriquement mise en œuvre, mais en pratique courante, son existence est difficile à démontrer compte tenu des enseignements toujours orientés dans l’Approche par Objectifs.
Denise Katolo Nankwaya, Samuel Bapidia Nzengu , Leyka Mukandu Basua Babintu, Augustin Tshitadi Makangu   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Participatory on-farm research and use of indigenous knowledge in the plain of reeds, Mekong Delta, Viet Nam [PDF]

, 1994
The ISA/FOS project conducts applied research with farmers to improve land reclamation techniques on highly acid sulfate soils in the Plain of Reeds, a dynamic pioneer zone in the Mekong delta in VietNam : Research topics and program were openly ...
Colliot, E., Husson, Olivier, Phung, Mai Thanh, Quyen, M.V.   +3 more
core  

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source