Results 11 to 20 of about 2,415,477 (301)
The Hidden Impact of the COVID-19 Pandemic on Routine Childhood Immunization Coverage in Cameroon
Background: The third round of the global pulse survey demonstrated that the abrupt and rapid progression of the COVID-19 pandemic significantly disrupted childhood immunization in many countries.
Yauba Saidu +14 more
doaj +1 more source
Introduction Cameroon’s Southwest Region (SW) has been hit by an armed conflict for over half a decade now, negatively affecting the region’s routine immunization and disease surveillance activities.
Andreas Ateke Njoh +10 more
doaj +1 more source
Applying real-world data from expanded-access (“compassionate use”) patients to drug development
Our drug development process has produced many life-saving medications, but patients experiencing rare diseases and similar conditions often are left with limited options for treatment.
June S. Wasser, David J. Greenblatt
doaj +1 more source
Background Immunization is regarded as one of the most cost-effective public health interventions in global health. However, its cost-effectiveness depends greatly on the knowledge and skills of vaccinators.
Yauba Saidu +17 more
doaj +1 more source
Patients with rare diseases often have limited or no options for approved treatments or participation in clinical trials. In such cases, expanded access (or “compassionate use”) provides a potential means of accessing unapproved investigational medicines.
Tobias B. Polak +10 more
doaj +1 more source
Background One crucial obstacle to attaining universal immunization coverage in Sub-Saharan Africa is the paucity of timely and high-quality data. This challenge, in part, stems from the fact that many frontline immunization staff in this part of the ...
Yauba Saidu +17 more
doaj +1 more source
Phage Therapy in the 21st Century: Is There Modern, Clinical Evidence of Phage-Mediated Efficacy?
Many bacteriophages are obligate killers of bacteria. That this property could be medically useful was first recognized over one hundred years ago, with 2021 being the 100-year anniversary of the first clinical phage therapy publication. Here we consider
Stephen T. Abedon +2 more
doaj +1 more source
The High “Cost” of Experimental Drugs Obtained Through Health Litigation in Brazil
BackgroundBrazilian patients have legal right to access unlicensed medicines undergoing clinical research, if there is evidence of efficacy and safety. This study investigated the occurrence of serious adverse events related to very high-cost medicines ...
Ricardo Eccard da Silva +4 more
doaj +1 more source
A Clean Energy Roadmap: Forging the Path Ahead [PDF]
Calls for better-aligned state policies, reduced market uncertainty, expanded power grid access, interagency and cross-sector collaboration, and a robust research-to-commercialization pipeline to boost investment in clean energy innovations and new ...
core +1 more source
Background: The achievement of neglected tropical diseases (NTDs) program goals depends on numerous factors, including the ability of national programs to use high-quality, timely data to inform their decision-making and program delivery.
Lakshmi Balachandran +18 more
doaj +1 more source

