Results 31 to 40 of about 2,415,477 (301)

Introduction of the pneumococcal conjugate vaccine in humanitarian and fragile contexts: Perspectives from stakeholders in four African countries

Human Vaccines & Immunotherapeutics
Childhood pneumonia causes a significant burden of preventable child morbidity and mortality in Chad, Guinea, Somalia/Somaliland, and South Sudan. Leaders from these countries have committed to reducing this burden and are preparing to introduce the ...
Baldeep K. Dhaliwal, Rose Weeks, Jasmine Huber, Aminata Fofana, Mohamed Bobe, Antoinette Demian Mbailamen, George Legge, Gassim Cisse, Anita Shet   +8 more
doaj   +1 more source

Proof-of-concept trial of an amniotic fluid-derived extracellular vesicle biologic for treating high risk patients with mild-to-moderate acute COVID-19 infection

Biomaterials and Biosystems, 2021
A pandemic brought on by COVID-19 has created a scalable health crisis. The search to help alleviate COVID-19-related complications through therapeutics has become a necessity.
Michael A. Bellio, Cassie Bennett, Alissa Arango, Aisha Khan, Xiumin Xu, Cesar Barrera, Vincent Friedewald, Maria Ines Mitrani   +7 more
doaj   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Cost of the typhoid conjugate vaccine introduction through an integrated campaign and follow-on routine immunization in Malawi

Vaccine: X
Malawi introduced typhoid conjugate vaccine (TCV) in 2023 through an integrated campaign delivering TCV alongside other vaccines and interventions (measles rubella vaccine (MRV), bivalent oral polio vaccine (OPV), and vitamin A Supplementation).
Frédéric Debellut, George Bello, Mike Chisema, Rouden Mkisi, Moses Kamzati, Clint Pecenka, Emmanuel Mugisha   +6 more
doaj   +1 more source

400 Exploring the Diversity of Expanded Access Patients at Michigan Medicine

Journal of Clinical and Translational Science, 2023
OBJECTIVES/GOALS: Lack of diversity within clinical trials is well known, but there is little data on the use of investigational products through other pathways, such as expanded access.
Misty Gravelin, Chelsea Frank, Laurie Rigan, Jeanne Wright, Kevin Weatherwax   +4 more
doaj   +1 more source

HIV Prevention in the Era of Expanded Treatment Access [PDF]

, 2004
Makes recommendations on how to forge a comprehensive response to the global AIDS epidemic by integrating prevention interventions into expanding treatment programs, and on new approaches to prevention that will be required as treatment access ...

core  

Traffic agents for improving QoS in mixed infrastructure and ad hoc modes wireless LAN [PDF]

, 2006
As an important complement to infrastructured wireless networks, mobile ad hoc networks (MANET) are more flexible in providing wireless access services, but more difficult in meeting different quality of service (QoS) requirements for mobile customers ...
A Hills, A Lackpour, DD Perkins, G Bianchi, H-R Chuang, Hai-Feng Yuan, Hsiao-Hwa Chen, IEEE Standards Board, JC Chen, JC Chen, K-C Huang, L Nagy, R-H Wu, Wen-Bing Yao, Y Lee, Yang Yang, Yong-Hua Song, Z Hadzi-Velkov   +17 more
core   +2 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Overcoming challenges and achieving high HPV vaccination uptake in Cameroon: lessons learned from a gender-neutral and single-dose program and community engagement

BMC Public Health
Introduction Human papillomavirus (HPV) is sexually transmissible and affects almost all sexually active people. The virus infects females and males, causing genital warts, cervical cancer, and oropharyngeal cancers in some. The disease burden is highest
Andreas Ateke Njoh, Dur-E-Nayab Waheed, Tchokfe Shalom Ndoula Josue Kedakse, Lionel Junior Ebongue, Eugene Justine Kongnyuy, Adidja Amani, Afizu Chrakoh Tambasho, Yauba Saidu, Mohamed II Kaba, Clovis Nchinjoh Sangwe, Herman Kenfack, Judith Seungue, Daniel Nebongo, Nadege Edwige Nnang, Alex Vorsters, Laurent Cleenewerck de Kiev   +15 more
doaj   +1 more source

The changing landscape of expanded access to investigational drugs for patients with unmet medical needs: ethical implications

Journal of Pharmaceutical Policy and Practice, 2017
When patients are told that standard medical treatment options have been exhausted, their treating physicians may start looking for promising new drugs that are not yet approved, and still under investigation.
Eline M. Bunnik, Nikkie Aarts, Suzanne van de Vathorst   +2 more
doaj   +1 more source