Results 81 to 90 of about 502,287 (298)
Nonuniformly expanding 1d maps with logarithmic singularities
, 2011 For a certain parametrized family of maps on the circle with critical points and logarithmic singularities where derivatives blow up to infinity, we construct a positive measure set of parameters corresponding to maps which exhibit nonuniformly expanding
Takahasi, Hiroki, Wang, Qiudong
core +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Synchronization versus stability of the invariant distribution for a class of globally coupled maps
, 2018 We study a class of globally coupled maps in the continuum limit, where the individual maps are expanding maps of the circle. The circle maps in question are such that the uncoupled system admits a unique absolutely continuous invariant measure (acim ...
Bálint, Péter +3 more
core +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
The Expanding Circle of Contract Law
SSRN Electronic Journal, 2016 People and corporations are increasingly held liable in private law for the external effects of their actions, in particular in cases that involve some fundamental aspect of “justice” such as severe violations of labour standards or threats to the environment.
openaire +2 more sources
, 2006 We present numerical verification of hyperbolic nature for chaotic attractor in a system of two coupled non-autonomous van der Pol oscillators (Kuznetsov, Phys. Rev. Lett., 95, 144101, 2005).
Afraimovich +22 more
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
"Anomaly" in n=infinity Alday-Maldacena Duality for Wavy Circle
, 2008 If the Alday-Maldacena version of string/gauge duality is formulated as an equivalence between double loop and area integrals a la arXiv: 0708.1625, then this pure geometric relation can be tested for various choices of n-side polygons.
Itoyama, H., Mironov, A., Morozov, A.
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source