Results 71 to 80 of about 9,061 (176)

Vaccines against extraintestinal pathogenic Escherichia coli (ExPEC): progress and challenges

Gut Microbes
The emergence of antimicrobial resistance (AMR) is a principal global health crisis projected to cause 10 million deaths annually worldwide by 2050. While the Gram-negative bacteria Escherichia coli is commonly found as a commensal microbe in the human gut, some strains are dangerously pathogenic, contributing to the highest AMR-associated mortality ...
Ling Qiu, Dylan Chirman, Justin R. Clark, Yikun Xing, Haroldo Hernandez Santos, Ellen E. Vaughan, Anthony W. Maresso   +6 more
openaire   +4 more sources

O-specific polysaccharide confers lysozyme resistance to extraintestinal pathogenic Escherichia coli

Virulence, 2018
Extraintestinal pathogenic Escherichia coli (ExPEC) is the leading cause of bloodstream and other extraintestinal infections in human and animals. The greatest challenge encountered by ExPEC during an infection is posed by the host defense mechanisms ...
Yinli Bao, Haobo Zhang, Xinxin Huang, Jiale Ma, Catherine M. Logue, Lisa K. Nolan, Ganwu Li   +6 more
doaj   +1 more source

Antibiotic resistance and virulence genes of extraintestinal pathogenic Escherichia coli from tropical estuary, south India

Journal of Infection in Developing Countries, 2015
Introduction: Escherichia coli strains can cause a variety of intestinal and extraintestinal diseases. Extraintestinal pathogenic E. coli (ExPEC) strains have the ability to cause severe extraintestinal infections.
Divya Sukumaran, Abdulla A Mohamed Hatha
doaj   +1 more source

Genomic epidemiology and lineage‐specific risk stratification of tet(X4)‐mediated tigecycline resistance along the pork production chain: A One Health perspective

iMetaOmics, Volume 3, Issue 2, June 2026.
Genome surveillance across a swine‐associated One Health continuum in China shows that slaughterhouses act as major enrichment nodes for tet(X4)‐mediated tigecycline resistance, driven by putative clonal transmission and stable plasmid backbones. Integrating global datasets enables lineage‐specific risk stratification, highlighting key control points ...
Qin Wang, Qiwu Yuan, Xuan Chen, Yujing Zhong, Ke Wu, Renqiao Wen, Luya Liu, Xiaoqin Wang, Cui Li, Hongning Wang, Changwei Lei   +10 more
wiley   +1 more source

Millennials' Work-Life Balance Expecations

, 2023
Work-life balance has become a prominent topic in literature and media, particularly in relation to the millennial generation. This first global generation, shaped by economic, social, and technological shifts, shares similar characteristics and attitudes worldwide.
openaire   +1 more source

Broad protective vaccination against systemic Escherichia coli with autotransporter antigens.

PLoS Pathogens, 2023
Extraintestinal pathogenic Escherichia coli (ExPEC) is the leading cause of adult life-threatening sepsis and urinary tract infections (UTI). The emergence and spread of multidrug-resistant (MDR) ExPEC strains result in a considerable amount of treatment
Yikun Xing, Justin R Clark, James D Chang, Dylan M Chirman, Sabrina Green, Jacob J Zulk, Joseph Jelinski, Kathryn A Patras, Anthony W Maresso   +8 more
doaj   +1 more source

Emerging Dissemination of blaCTX‐M‐65 in Bovine E. coli in Spain Associated With IncHI2 Plasmids

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
The resistome in ESBL/AmpC‐producing E. coli in livestock was diverse and dominated by plasmid‐borne genes Detection of host‐independent dissemination of AMR determinants mediated by shared plasmid types First report in Spanish cattle of blaCTX‐M‐65 on IncHI2 plasmids, an under‐reported ESBL in Europe Identification of potentially zoonotic clones in ...
Medelin Ocejo, Beatriz Oporto, Ana Hurtado   +2 more
wiley   +1 more source

Integrative Modular, Network‐Based, and Machine Learning Framework for Predicting Accessory Genome Functions and Virulence in Escherichia coli O157:H7

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
An analysis of the accessory genomes from 77 Escherichia coli O157:H7 strains using network and machine learning techniques uncovers modular communities of plasmid‐related virulence associated with IncF replicons. Accessory markers that are not directly linked to toxin genes can effectively predict the virulence status with an AUC of 0.85, facilitating
Sydney Menzeko Gambushe, Oliver Tendayi Zishiri   +1 more
wiley   +1 more source

Tandemly duplicated TaERF109 genes confer drought tolerance and post‐drought recovery in wheat

Journal of Integrative Plant Biology, Volume 68, Issue 6, Page 1744-1761, June 2026.
Tandemly duplicated TaERF109 transcription factor genes in wheat modulate growth traits and enhance drought tolerance by regulating the TaMADS56 transcription factor gene, cytokinin biosynthesis‐related genes, and nicotianamine synthase genes, revealing the critical role of tandemly duplicated genes in the coordination of stress responses and ...
Jun Chen, Shang Zhao, Wenjing Li, Chunxiao Wang, Yuan Gao, Zihan Yang, Yongbin Zhou, Ming Chen, Zhaoshi Xu, Youzhi Ma   +9 more
wiley   +1 more source

Extra-intestinal pathogenic Escherichia coli: A combination of virulence with antibiotic resistance.

Frontiers in Microbiology, 2012
Escherichia coli represents an incredible versatile and diverse enterobacterial species and can be subdivided into the following; i) intestinal non-pathogenic, commensal isolates. ii) intestinal pathogenic isolates and iii) extraintestinal pathogenic or
Johann ePitout
doaj   +1 more source