Results 101 to 110 of about 2,833,538 (233)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Experience-based Modifications of the Bed Band ReAlised through Co-dEsign (EMBRACE)

open access: yesBMJ Open Quality
Background Upper body limitations are a common disability in neurological conditions including stroke and multiple sclerosis. Care of patients with upper body limitations while in bed involves positioning techniques to maximise comfort and independence ...
Michelle Beattie   +4 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

From co-design to co-teaching: a comprehensive approach to an integrated AI curriculum in middle school STEM education

open access: yesSmart Learning Environments
Co-design and co-teaching are practical approaches for teachers with varying experiences to get involved in integrating AI curriculum with STEM subjects.
Keunjae Kim, Kyungbin Kwon
doaj   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Community-based participatory-research through co-design: supporting collaboration from all sides of disability

open access: yesResearch Involvement and Engagement
Background As co-design and community-based participatory research gain traction in health and disability, the challenges and benefits of collaboratively conducting research need to be considered.
Cloe Benz   +7 more
doaj   +1 more source

Improvement and operating experience of the AE64.3A gas turbine installed in CCPP of Vlore [PDF]

open access: yes, 2011
Cilj je ovoga rada ukratko predstaviti poboljšanja i optimizaciju plinske turbine AE64.3A u projektnoj fazi i također rezultate dobivene ispitivanjem tijekom puštanja u pogon u termoelektrani Vlore.
Klodian Gumeni
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Development of embodied listening studies with multimodal and wearable haptic interfaces for hearing accessibility in music

open access: yesFrontiers in Computer Science
IntroductionThe intersection of hearing accessibility and music research offers limited representations of the Deaf and Hard of Hearing (DHH) individuals, specifically as artists. This article presents inclusive design practices for hearing accessibility
Doga Cavdir
doaj   +1 more source

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