Results 81 to 90 of about 2,833,538 (233)

Involving service users in the qualitative analysis of patient narratives to support healthcare quality improvement

Research Involvement and Engagement, 2019
Plain English summary Patient or user involvement in health research is well-established but is often limited to advising on research questions and design, leaving researchers to collect and analyse ‘data’ (which in this paper means written copies of ...
Louise Locock, Susan Kirkpatrick, Lucy Brading, Gordon Sturmey, Jocelyn Cornwell, Neil Churchill, Glenn Robert   +6 more
doaj   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Testing accelerated experience-based co-design: a qualitative study of using a national archive of patient experience narrative interviews to promote rapid patient-centred service improvement

Health Services and Delivery Research, 2014
Background: Measuring, understanding and improving patients’ experiences is of central importance to health care systems, but there is debate about the best methods for gathering and understanding patient experiences and how to then use them to improve ...
Louise Locock, Glenn Robert, Annette Boaz, Sonia Vougioukalou, Caroline Shuldham, Jonathan Fielden, Sue Ziebland, Melanie Gager, Ruth Tollyfield, John Pearcey   +9 more
doaj   +1 more source

The Mixed Reality Toolkit as the Next Step in the Mass Customization Co-Design Experience

International Journal of Industrial Engineering and Management, 2019
The mass customization (MC) toolkit is the major enabler of relational value for consumers. Not a new concept, but nascent in the context of the MC co-design experience, mixed reality (MR) merges the real and virtual world.
Frances Turner, Ian Welch
doaj   +1 more source

‘Islands in the stream’ – causeways or compromise? [PDF]

, 2010
In recent years, policy drivers have given a strategic push towards encouraging ‘employer-led’ work based learning in Higher Education. For example, Leitch ( 2006?) and other key policy makers advocate institutional change and reform in HE to respond to ...
Leonard, Dilys T., Talbot, Jon
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Improving the Aerospace Capstone Design Experience Through Simulation Based Learning [PDF]

, 2012
A key role of universities is to prepare students to work in their chosen profession upon completion of their degree program. Engineering capstone design courses are often the only required courses that challenge students to draw on nearly all of the ...
Butler, Wm. Michael, Goff, Richard, Pant, Rajkumar, Steinhauer, Heidi, Terpenny, Janis, Terpenny, Janis   +5 more
core   +3 more sources

An ontology co-design method for the co-creation of a continuous care ontology [PDF]

, 2014
Ontology engineering methodologies tend to emphasize the role of the knowledge engineer or require a very active role of domain experts. In this paper, a participatory ontology engineering method is described that holds the middle ground between these ...
Ackaert, Ann, Bleumers, Lizzy, De Turck, Filip, De Zutter, Saar, Duysburgh, Pieter, Jacobs, An, Ongenae, Femke, Sulmon, Nicky, Verstichel, Stijn, Verstraete, Mathijs   +9 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source