Results 91 to 100 of about 5,358,410 (308)

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

Measuring Uncertainty in Games: Design and Preliminary Validation [PDF]

open access: yes, 2017
Uncertainty is an important element of game play, which is widely believed to act as a precondition for player experience (PX). To investigate the concept and examine its relation to other PX concepts, we should be able to measure it.
Cairns, P.   +3 more
core   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

“Anyone can co-design?”: A case study synthesis of six experience-based co-design (EBCD) projects for healthcare systems improvement in New South Wales, Australia

open access: yesPatient Experience Journal, 2019
Experience-based co-design (EBCD) is a quality improvement approach that is being used internationally to bring service users and health professionals together to improve healthcare experiences, systems and processes.
Tara Dimopoulos-Bick   +11 more
doaj  

Blended Learning: Architectural Design Studio Experiences Using Housing in Istanbul

open access: yesJournal of Problem Based Learning in Higher Education, 2017
This paper presents how a blended learning pedagogic model is integrated into an architectural design studio for housing in the Faculty of Architecture in Istanbul Technical University adapting the problem-based learning process.
Yasemin Alkiser Bregger
doaj   +1 more source

Neural Network architectures design by Cellular Automata evolution [PDF]

open access: yes, 2000
4th Conference of Systemics Cybernetics and Informatics. Orlando, 23-26 July 2000The design of the architecture is a crucial step in the successful application of a neural network.
Galván, Inés M.   +3 more
core   +1 more source

Formal Reasoning Using an Iterative Approach with an Integrated Web IDE

open access: yes, 2015
This paper summarizes our experience in communicating the elements of reasoning about correctness, and the central role of formal specifications in reasoning about modular, component-based software using a language and an integrated Web IDE designed for ...
Durkee, Blair   +6 more
core   +2 more sources

Problem-based learning spanning real and virtual words: a case study in Second Life [PDF]

open access: yes, 2008
There is a growing use of immersive virtual environments for educational purposes. However, much of this activity is not yet documented in the public domain, or is descriptive rather than analytical.
Good, Judith   +2 more
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

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