Results 81 to 90 of about 1,670,412 (309)

Model-based Design of Experiments for Large Dataset

open access: yes, 2021
The first part of this thesis presents the motivation for adapting ideas and methods from the theory of the model-based optimal design of experiments in the context of Big Data while guarding against different sources of bias. In particular, the key focus is on the issue of guarding against bias from confounders and how to use the theory of the design ...
openaire   +2 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Framing Behavioural Change through Place-Based Initiatives: Repair-led design strategies for environmental restoration

open access: yes, 2023
Design’s agency to enact positive change in conditions of climate change has been promoted by theorists and practitioners, but it has yet to be extensively employed as a process of systemic adaptation and restoration.
Smith, Skye, Kalantidou, Eleni
core  

Using patients’ experiences to identify priorities for quality improvement in breast cancer care: patient narratives, surveys or both?

open access: yesBMC Health Services Research, 2012
Background Patients’ experiences have become central to assessing the performance of healthcare systems worldwide and are increasingly being used to inform quality improvement processes.
Tsianakas Vicki   +7 more
doaj   +1 more source

Experiments on adaptation-guided retrieval in case-based design [PDF]

open access: yes, 1995
Case-based reasoning (CBR) has been applied with some success to complex planning and design tasks. In such systems, the best case is retrieved and adapted to solve a particular target problem. Often, the best case is that which can be most easily adapted to the target problem (as the overhead in adaptation is generally very high). Standard CBR systems
Smyth, Barry, Keane, Mark T.
openaire   +2 more sources

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

open access: yesFEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Using a Process Knowledge Based CAD for a More Robust Response to Demands for Quotation [PDF]

open access: yes, 2009
Organised by: Cranfield UniversityOut of 100 hours of engineering work, only 20 are dedicated to real engineering and 80 are spent on what is considered routine work.
Sagot, J. C., Gomes, S., Toussaint, L.
core  

Public aquatic facilities as enablers of human-marine active interactions: An affordance-based conceptual approach [PDF]

open access: yesArchitecture Papers of the Faculty of Architecture and Design STU
A key feature of urban regeneration projects along waterfronts is the focus on reconnecting with the wider urban environment. However, the relationship with the aquatic environment is less explored, as are attempts to promote a deeper and more varied ...
Luis Carlos Martins Mestrinho, MSc.
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

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