Results 101 to 110 of about 5,358,410 (308)

Experience-Based Co-Design: Tackling common challenges

The Journal of Health Design, 2018
There has been a surge in experience-based co-design (EBCD) efforts for quality improvement in health care and systems design globally. The authors identify common, shared challenges with using EBCD and their subsequent impact.
Tara Dimopoulos-Bick, Paresh Dawda, Lynne Maher, Raj Verma, Victoria Palmer   +4 more
doaj  

Reflections on the opportunities and challenges of applying experience‐based co‐design (EBCD) to phase 1 clinical trials in oncology

Health Expectations
Background Experience‐Based Co‐Design (EBCD) is a multi‐stage participatory action research process which was developed originally to increase patient involvement in service improvement initiatives.
Nils Graber, Nina Canova, Denise Bryant‐Lukosius, Glenn Robert, Blanca Navarro‐Rodrigo, Lionel Trueb, George Coukos, Manuela Eicher, Tourane Corbière, Sara Colomer‐Lahiguera   +9 more
doaj   +1 more source

Encouraging Effective Group Work: The pedagogical challenges involved in designing a staff workshop [PDF]

, 2012
This paper discusses two main pedagogical challenges involved in designing a workshop for staff in the Schools of Arts and Social Sciences. While it may be simple to prepare a linear, teacher-driven presentation which can be delivered to an audience of ...
Pamplin, M.
core  

Model-based Design of Experiments for Large Dataset

, 2021
The first part of this thesis presents the motivation for adapting ideas and methods from the theory of the model-based optimal design of experiments in the context of Big Data while guarding against different sources of bias. In particular, the key focus is on the issue of guarding against bias from confounders and how to use the theory of the design ...
openaire   +2 more sources

Experiences of patients with a disability in receiving primary health care: Using experience-based design for quality improvement. [PDF]

Can Fam Physician, 2021
Walji S, Carroll JC, Haber C.
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

OntoEng: A design method for ontology engineering in information systems [PDF]

, 2009
This paper addresses the design problem relating to ontology engineering in the discipline of information systems. Ontology engineering is a realm that covers issues related to ontology development and use throughout its life span.
Al-Debei, MM, Fitzgerald, G
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Testing accelerated experience-based co-design: a qualitative study of using a national archive of patient experience narrative interviews to promote rapid patient-centred service improvement

Health Services and Delivery Research, 2014
Background: Measuring, understanding and improving patients’ experiences is of central importance to health care systems, but there is debate about the best methods for gathering and understanding patient experiences and how to then use them to improve ...
Louise Locock, Glenn Robert, Annette Boaz, Sonia Vougioukalou, Caroline Shuldham, Jonathan Fielden, Sue Ziebland, Melanie Gager, Ruth Tollyfield, John Pearcey   +9 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source