Results 71 to 80 of about 49,920 (245)

Inosina previne a resposta inflamatória e nociceptiva induzida pelo modelo experimental de esclerose múltipla [PDF]

open access: yes, 2015
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Neurociências, Florianópolis, 2015.A Esclerose Múltipla (EM) é uma doença autoimune mediada por linfócitos T e caracterizada por ...
Junqueira, Stella Célio
core  

Behavioral investigation of mice with experimental autoimmune encephalomyelitis

open access: yesArquivos de Neuro-Psiquiatria, 2011
Multiple sclerosis is a neuroinflammatory disease that results in serious neurological disability. Besides physical impairment, behavioral symptoms are also common in patients with multiple sclerosis.
David Henrique Rodrigues   +6 more
doaj   +1 more source

Emodin attenuates inflammation and demyelination in experimental autoimmune encephalomyelitis

open access: yesNeural Regeneration Research, 2023
Emodin, a substance extracted from herbs such as rhubarb, has a protective effect on the central nervous system. However, the potential therapeutic effect of emodin in the context of multiple sclerosis remains unknown.
Yue-Ran Cui   +4 more
doaj   +1 more source

Suppression of Experimental Autoimmune Encephalomyelitis by Ghrelin [PDF]

open access: yesThe Journal of Immunology, 2009
Abstract Ghrelin is a recently identified gastric hormone that displays strong growth hormone-releasing activity mediated by the growth hormone secretagogue receptor. While this unique endogenous peptide participates in the regulation of energy homeostasis, increases food intake, and decreases energy expenditure, its ability to ...
Michael-Mark, Theil   +14 more
openaire   +2 more sources

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

open access: yesBMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou   +6 more
wiley   +1 more source

c-Jun N-Terminal Kinase as a Therapeutic Target in Experimental Autoimmune Encephalomyelitis. [PDF]

open access: yes, 2020
c-Jun N-terminal kinase (JNK) is upregulated during multiple sclerosis relapses and at the peak of experimental autoimmune encephalomyelitis (EAE).
Bagnoud, Maud   +17 more
core   +1 more source

A Tripartite Model for EBV‐Driven Multiple Sclerosis: B Cell Survival, Altered Self‐Presentation, and HLA‐DR15‐Restricted T Cell Cross‐Reactivity

open access: yesiNew Medicine, EarlyView.
ABSTRACT This commentary integrates findings from three recent Cell reports to establish a unified mechanistic model of multiple sclerosis (MS) driven by the interplay between Epstein‐Barr virus (EBV) and the HLA‐DR15 genotype. EBV promotes CNS autoimmunity through three distinct but intersecting mechanisms.
Fang Zhu   +2 more
wiley   +1 more source

Understanding the Pathogenesis of Neuroinflammation using Magnetic Resonance Imaging [PDF]

open access: yes, 2011
A non-invasive view of the brain with the aid of magnetic resonance imaging (MRI) is invaluable for studying pathological processes during autoimmune encephalomyelitis.
Waiczies, Sonia   +3 more
core  

Anti-inflammatory effect and mechanisms of Huangqi glycoprotein in treating experimental autoimmune encephalomyelitis

open access: yes, 2017
Huangqi glycoprotein (HQGP) is prepared from Astragalus membranaceus by ammonium sulfate precipitation. It was indicated that HQGP has an immunoregulatory effect.
Baoguo Xiao   +9 more
core   +1 more source

Improving enteral nutrition in patients requiring neurological intensive care unit care: A retrospective study on a novel bedside nasointestinal tube placement technique

open access: yesNutrition in Clinical Practice, EarlyView.
Abstract Background This study aimed to develop and assess a bedside nasojejunal tube placement technique designed for resource‐limited settings to address the specific challenges of enteral nutrition (EN) delivery in neurocritical care patients, particularly those at high risk of reflux and aspiration. The technique sought to overcome the drawbacks of
Niuchenglin   +5 more
wiley   +1 more source

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