Results 71 to 80 of about 40,848 (156)

Trends in Clinical Indications for Plasma Exchange in Adult Patients Between 2008 and 2024 in Bogotá, Colombia

Journal of Clinical Apheresis, Volume 41, Issue 4, August 2026.
ABSTRACT This multicenter retrospective study aimed to describe temporal trends in clinical indications for plasma exchange (PE) in adult patients at four quaternary‐care hospitals in Bogotá (2008–2024) and to examine their distribution across successive ASFA guideline editions.
Edgar Julián Reyes, Federico Tovar‐Avendaño, Camilo Alberto Gonzalez‐Gonzalez, Diana Carolina Vargas‐Angel, Jorge Pulido, Paula Violeta Rodríguez, Deiner‐Yivelson Muñoz‐Delgado, Kateir Contreras‐Villamizar   +7 more
wiley   +1 more source

Decoding Akkermansia muciniphila Effector Biology: From Microbial Molecules to Host Outcomes

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Schematic overview of the proposed gut–brain axis mechanisms linking Akkermansia muciniphila to host outcomes. A. muciniphila‐derived signals, including SCFAs and P9/GLP‐1‐related endocrine pathways, may influence epithelial barrier integrity, inflammatory responses, systemic immune signaling, and neural communication through the enteric nervous system,
Amir Arsalan Ghahari, Ainur Sadykova, Salim Davlatov, Mukaddas Xusanova, Gulrukh Indiaminova, Furkat Sobirov, Mirzamakhmud Shadmanov, Umidjon Maxamatov, Patkhiddin Nishonov, Seyed Davar Siadat   +9 more
wiley   +1 more source

Activity-attenuated serum albumin-fused interleukin-33 suppresses experimental autoimmune encephalomyelitis

Cell Reports Medicine
Summary: Interleukin-33 (IL-33) is an immunoregulatory cytokine that moderately suppresses experimental autoimmune encephalomyelitis (EAE), a murine model of multiple sclerosis (MS).
Erica Budina, Joseph W. Reda, Shijie Cao, Elyse A. Watkins, Ani Solanki, Mindy Nguyen, Phillip S. Ang, J. Emiliano Gómez Medellín, Hye-Rin Chun, Colleen R. Foley, Brendan T.K. Berg, Ha-Na Shim, Kevin Hultgren, Zahra Khosravi, Arjun Dhar, Suzana Gomes, Andrew C. Tremain, Ako Ishihara, Jun Ishihara, Jeffrey A. Hubbell   +19 more
doaj   +1 more source

SIRT Family: Biological Functions and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang, Feng‐Li Jiang, Fang‐Yuan Zhang, Dong‐Hui Huang, Xiao‐Ying Li, Song Gao, Hua You, Qi‐Jun Wu, Huan‐Huan Chen, Ting‐Ting Gong   +9 more
wiley   +1 more source

Lymphatic Endothelial Cells in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
Lymphatic endothelial cells (LECs) are dynamic regulators of tissue homeostasis and disease remodeling. In the healthy state, LECs coordinate interstitial fluid drainage, intestinal lipid transport, and immune trafficking and tolerance. Across disease settings, however, these same programs become maladaptively reprogrammed, contributing to barrier ...
Du Tang, Wang Lin, Hengyang Liu, Jixin Zhong, Shiliang Li, Xiaoquan Rao   +5 more
wiley   +1 more source

Experimental autoimmune encephalomyelitis

Biomedical Journal, 2015
Jean Kanellopoulos
doaj   +1 more source

Modeling the lung‒brain axis in critical illness: Multifactorial crosstalk through organoids and organ‐on‐a‐chip system

VIEW, Volume 7, Issue 4, August 2026.
Patients in intensive care units often experience lung injuries, complicated by brain problems. Advanced laboratory tools, organoids, and organs‐on‐chips facilitated the study of multiorgan interactions, help us understand the communication between the lungs and brain.
Wanyi Zhang, Ting Wang, Mengying Yao, Longxiang Su, Lixin Xie, Pan Pan   +5 more
wiley   +1 more source

Infection control in the brain and the eye

Acta Ophthalmologica, Volume 104, Issue 5, Page e478-e490, August 2026.
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester, Paul G. McMenamin, Samantha J. Dando   +2 more
wiley   +1 more source

Update on the Incidence of Paediatric Multiple Sclerosis, Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease, Aquaporin‐4 Antibody–Positive Neuromyelitis Optica Spectrum Disorder, and Other Acquired Demyelinating Syndromes in the Netherlands, 2017–2025, Including the COVID‐19 Pandemic

European Journal of Neurology, Volume 33, Issue 8, August 2026.
ABSTRACT Background Acquired demyelinating syndromes (ADS) in children include multiple sclerosis (MS), myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), aquaporin 4 antibody‐positive neuromyelitis optica spectrum disorder (AQP4+ NMOSD), and other seronegative disorders.
Sandy Molenaar, Michiel S. J. Buijze, Arlette L. Bruijstens, Yu Yi M. Wong, Maud A. Quist, C. Louk de Mol, Beatrijs H. A. Wokke, Rinze F. Neuteboom, Dutch Study Group for Paediatric Multiple Sclerosis and Acute Disseminated Encephalomyelitis   +8 more
wiley   +1 more source

Preventive effect of injections of vitamin D on the levels of Klotho in the brain tissue of female lewis rats with experimental autoimmune ensephalomyelitis

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2019
Introdution: The aim of this study was to investigate the effect of vitamin D supplementation on Klotho levels of the brain tissue. Methods: In this laboratory experimental study, 25 female Lewis rats, after 2 weeks adaptation to lab environmental, were ...
seyedeh fatemeh fatemi, zia fallah mohammadi, vahid Talebi, Sayed mojtaba Hosseini   +3 more
doaj