Results 171 to 180 of about 16,072 (215)
Some of the next articles are maybe not open access.
Immunobiology of experimental cutaneous leishmaniasis
Parasitology Today, 1995The study of the murine model of infection with Leishmania major is providing important insights into the understanding of the complex interactions between the host and intracellular pathogens. Using this model system, basic research is actively leading to the identification of host factors promoting or circumventing the development of immunity to L ...
G, Milon, G, Del Giudice, J A, Louis
openaire +2 more sources
Natural Killer Activity in Experimental Cutaneous Leishmaniasis
International Archives of Allergy and Immunology, 1984Studies were performed to determine the role of natural killer (NK) cell cytotoxicity in experimental cutaneous leishmaniasis. Analysis of a possible correlation between in vitro NK cell activity and in vivo susceptibility to <i>Leishmania mexicana </i>infection showed that there is no relationship between the degree of NK reactivity to YAC-
F, Merino, I, Cruz
openaire +2 more sources
The American Journal of Tropical Medicine and Hygiene, 1982
Abstract Leishmania tropica infections in mice provide models for the study of non-healing leishmanial infections similar to diffuse cutaneous leishmaniasis (DCL) in man. BALB/c mice infected with L. tropica developed large non-healing primary lesions as well as multiple metastatic lesions on the feet, face and ears.
P A, Scott, J P, Farrell
openaire +2 more sources
Abstract Leishmania tropica infections in mice provide models for the study of non-healing leishmanial infections similar to diffuse cutaneous leishmaniasis (DCL) in man. BALB/c mice infected with L. tropica developed large non-healing primary lesions as well as multiple metastatic lesions on the feet, face and ears.
P A, Scott, J P, Farrell
openaire +2 more sources
Aminosidine ointments for the treatment of experimental cutaneous leishmaniasis
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1994A 15% aminosidine sulphate (AS)/10% urea/white soft paraffin (WSP) ointment cured all Leishmania major lesions on Balb/C mice following topical application for 10 d. Some relapses were observed 10 weeks after treatment. AS alone in WSP ointment was also highly effective.
R A, Neal +3 more
openaire +2 more sources
Neuropeptide Y concentrations in experimental Leishmania major cutaneous leishmaniasis
NeuroReport, 1998Neuropeptide Y (NPY) concentrations were investigated by radioimmunoassay and immunohistochemistry in a murine model of cutaneous leishmaniasis, using a susceptible (BALB/c) and a resistant (C57BL/6) mouse strain. The analyses were performed on the skin, secondary lymphoid organs and dorsal root ganglia (DRG) at 1, 3, 6 and 9 weeks postinfection.
A A, Ahmed +3 more
openaire +2 more sources
Cell-mediated immunity in experimental cutaneous leishmaniasis
Parasitology Today, 1986Forms of cutaneous leishmaniasis are caused by Leishmania major, L. tropica, L. mexicana, L. amazonensis and L. panamensis. Like all leishmanial species, these are obligate intracellular parasites of the mononuclear phagocyte system, with a restricted range of vertebrate hosts including humans, dogs, rodents and arboreal animals.
openaire +2 more sources
Experimental murine infection with the diffuse cutaneous leishmaniasis strain, Isabel
Annals of Tropical Medicine & Parasitology, 1987Infection with the Isabel strain of Leishmania has been followed in several inbred strains of mice over an extended period. The mouse strains segregate into three major types with respect to susceptibility to infection: BALB/c, BALB.B and SWR/J are susceptible; DBA/1J is intermediate; and C57BL/6, C57BL/10, DBA/2J and B10.D2 are resistant.
B A, Shaw, J B, Grayson, E A, Petersen
openaire +2 more sources
The Effect of BCG on Experimental Cutaneous Leishmaniasis in Mice
The Journal of Immunology, 1977Abstract The effect of administration of live Bacillus Calmette-Guerin (BCG), a nonspecific immunostimulant, on the course of experimental cutaneous leishmaniasis in mice was investigated. BALB/c mice were injected in the footpad with Leishmania tropica, NIH S-strain; in mice that were not pretreated with BCG this produced a reproducible
Weintraub, J, Weinbaum, F I
openaire +2 more sources
Immunopathology of experimental cutaneous leishmaniasis.
The American journal of pathology, 1984Relatively susceptible BALB/c and relatively resistant A/J mice were infected subcutaneously in the right hind footpad with promastigotes of Leishmania mexicana amazonensis. A large localized lesion developed within 2 months after infection in the BALB/c mice, while A/J mice exhibited a small discrete fibrotic nodule.
Andrade, Z A +3 more
openaire +1 more source
Antigen presentation by epidermal langerhans cells in experimental cutaneous leishmaniasis
Parasite Immunology, 1994SUMMARYCutaneous leishmaniasis is a disease induced by intradermal injection of leishmania promastigotes. Since the first cells the parasite encounters are those of the skin, the involvement of this organ in the early immune response might be relevant to the outcome of the disease. In this study we examined the ability of epidermal langerhans cells (LC)
O, Axelrod, S, Klaus, S, Frankenburg
openaire +2 more sources