Results 31 to 40 of about 144,130 (263)

Velocity distribution measurements in a fishway like open channel by Laser Doppler Anemometry (LDA)

EPJ Web of Conferences, 2016
Experiments in an open channel flume with placing a vertical half cylinder barrier have been performed in order to investigate how the upstream velocity profiles are affected by a barrier.
Sayeed-Bin-Asad S.M., Lundström T. S., Andersson A.G., Hellström J. G. I.   +3 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Experimental Evaluation of Rolling Resistance in Omnidirectional Wheels Under Quasi-Static Conditions

Sensors
This paper presents the results of experimental research on rolling resistance forces occurring during the motion of omnidirectional wheels equipped with dual rows of passive rollers. Due to the complexity of wheel–surface interactions and the stochastic
Sławomir Duda, Grzegorz Gembalczyk, Tomasz Machoczek, Zygmunt Kowalik   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Acoustic Signature Analysis and Sound Source Localization for a Three-Phase AC Induction Motor

Energies, 2021
As part of the recent electrification of the transportation industry, internal combustion engines are being coupled with or replaced by electric motors.
Anand Krishnasarma, Seyed Jamaleddin Mostafavi Yazdi, Allan Taylor, Daniel Ludwigsen, Javad Baqersad   +4 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Experimental characterization of the compression-compression fatigue performance in 3D printed flexible honeycombs

Materials Research Express
Cellular materials are gaining popularity as constituent materials in end-use products due to their tunable stiffness and energy absorption capabilities.
Amador Chapa, E Cuan-Urquizo, A Roman-Flores, P D Urbina-Coronado   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source