Results 41 to 50 of about 8,549,066 (299)

Experimental models of epilepsy

Medicinski pregled, 2004
Introduction An epileptic seizure is a clinical event and epilepsy is rather a group of symptoms than a disease. The main features all epilepsies have in common include: spontaneous occurrence, repetitiveness, and ictal correlation within the EEG. Epilepsies are manifested with distinct EEG changes, requiring exact clinical definition and consequential
Olivera P, Stanojlović, Dragana P, Zivanović   +1 more
openaire   +3 more sources

MYCN Amplification in RB1‐Inactivated Retinoblastoma: Association With High‐Risk Features

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background MYCN amplification occurs in a subset of retinoblastoma cases, both with and without RB1 inactivation. It has been suggested that retinoblastomas with MYCN amplification represent a distinct entity with more aggressive clinical behavior.
Kyriaki Papaioannou, Regina Kubica, Karen Fischhuber, Jasmin Beygo, Madlen Reschke, Petra Ritter‐Sovinz, Eva Biewald, Petra Ketteler, Dietmar Lohmann, Deniz Kanber   +9 more
wiley   +1 more source

Advances in Innate Immunity to Overcome Immune Rejection during Xenotransplantation

Cells, 2022
Transplantation is an effective approach for treating end-stage organ failure. There has been a long-standing interest in xenotransplantation as a means of increasing the number of available organs.
Tian-Yu Lu, Xue-Ling Xu, Xu-Guang Du, Jin-Hua Wei, Jia-Nan Yu, Shou-Long Deng, Chuan Qin   +6 more
doaj   +1 more source

Experimental models of stress

Dialogues in Clinical Neuroscience, 2006
Illustrating the complexity of the stress response and its multifaceted manifestations is the leading idea of this overview of experimental paradigms used for stress induction in laboratory animals. The description of key features of models based on naturalistic stressors, pharmacological challenges, and genomic manipulations is complemented by ...
Vladimir K, Patchev, Alexandre V, Patchev   +1 more
openaire   +3 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

The Poisson-Boltzmann model for implicit solvation of electrolyte solutions: Quantum chemical implementation and assessment via Sechenov coefficients. [PDF]

, 2019
We present the theory and implementation of a Poisson-Boltzmann implicit solvation model for electrolyte solutions. This model can be combined with arbitrary electronic structure methods that provide an accurate charge density of the solute.
Briggs W. L., Christopher J. Stein, Debye P., John M. Herbert, Martin Head-Gordon, Pedregosa F., Sechenov I., Stern O.   +7 more
core   +2 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Nuclear Attenuation of high energy two-hadron system in the string model [PDF]

, 2006
Nuclear attenuation of the two-hadron system is considered in the string model. The two-scale model and its improved version with two different choices of constituent formation time and sets of parameters obtained earlier for the single hadron ...
A. Accardi, A. Airapetian, A. Airapetian, A. Bialas, A. Bialas, A. Majumder, B. Kopeliovich, E. Wang, E.J. Moniz, G. Davidenko, J. Adams, J. Ashman, J. Czyzewski, J. Czyzewski, L. Grigoryan, M. Gyulassy, N. Akopov, N. Akopov, P. Nezza Di, T. Falter, T. Falter, X.-N. Wang, Z. Akopov   +22 more
core   +2 more sources

Experimental Models of Pancreatitis

Clinical Endoscopy, 2014
Acute pancreatitis is an inflammatory disease characterized by interstitial edema, inflammatory cell infiltration, and acinar cell necrosis, depending on its severity. Regardless of the extent of tissue injury, acute pancreatitis is a completely reversible process with evident normal tissue architecture after recovery. Its pathogenic mechanism has been
Hyun, Jong Jin, Lee, Hong Sik
openaire   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source