Results 51 to 60 of about 8,549,066 (299)

CpG-ODN Facilitates Effective Intratracheal Immunization and Recall of Memory against Neoantigen-Expressing Alveolar Cells

Frontiers in Immunology, 2017
Intrapulmonary immune reactions are impaired by the tolerogenic environment of the lung. This is manifested by the absence of effective endogenous T cell responses upon neoantigen expression.
Mathias Riehn, Marcin Cebula, Hansjörg Hauser, Dagmar Wirth, Dagmar Wirth   +4 more
doaj   +1 more source

Development of radiation countermeasure agents for acute radiation syndromes

Animal Models and Experimental Medicine, 2023
The risk of internal and external exposure to ionizing radiation (IR) has increased alongside the development and implementation of nuclear technology. Therefore, serious security issues have emerged globally, and there has been an increase in the number
Bowen Guan, Deguan Li, Aimin Meng
doaj   +1 more source

Possible Experimental Test of Continuous Medium Model for Fractal Media

, 2005
We use the fractional integrals to describe fractal media. We consider the fractal media as special ("fractional") continuous media. We discuss the possible experimental testing of the continuous medium model for fractal media that is suggested in Phys ...
Avnir, Bale, Beran, Christensen, Collins, Katz, Le Mehaute, Mandelbrot, Pfeifer, Ren, Samko, Samko, Schaefer, Schaefer, Schroeder, Tarasov, Tarasov, Tarasov, Tarasov, Tarasov, Vasily E. Tarasov, Zaslavsky, Zaslavsky   +22 more
core   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Internally Electrodynamic Particle Model: Its Experimental Basis and Its Predictions

, 2010
The internally electrodynamic (IED) particle model was derived based on overall experimental observations, with the IED process itself being built directly on three experimental facts, a) electric charges present with all material particles, b) an ...
A. H. Bucherer, A. Tonomura, B. Brezger, C. D. Anderson, C. Davisson, Ch. E. Guye, D. Griffiths, D. P. Mitchell, E. Schrödinger, F. Joliot, F. R. Elder, G. P. Thomson, G. T. Gillies, H. Halban, H.-D. Doebner, I. Estermann, J. Stark, J. Thibaud, J. W. M. DuMond, J. X. Zheng-Johansson, J. X. Zheng-Johansson, J. X. Zheng-Johansson, J. X. Zheng-Johansson, J. X. Zheng-Johansson, J. X. Zheng-Johansson, J. X. Zheng-Johansson, J. X. Zheng-Johansson, L. Broglie de, M. Planck, O. Klemperer, P. A. M. Dirac, P. G. Merli, P. M. S. Blackett, W. Kaufmann, W. M. Elsasser, Y. Yoshizawa   +35 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Torque control of switched reluctance motors [PDF]

, 2011
This paper presents the performance of an instantaneous torque control method. The simulation and experimental results illustrate the capability of Switched Reluctance Motors (SRM) being used in the motor drive industry. Based on experimental data, the
García García, Alfonso, Morón Fernández, Carlos, Somolinos Sánchez, José Andrés, Tremps Guerra, Enrique   +3 more
core   +1 more source

Doping induced inhomogeneity in high-Tc superconductors

, 2000
Doping and disorder are inseparable in the superconducting cuprates. Assuming the simplest possible disordered doping, we construct a semiphenomenological model and analyze its experimental consequences. Among the affected experimental quantities are the
Alexander V. Balatsky, Balatsky, Gofron, Goldman, Ivar Martin, Madhavan, Shen   +6 more
core   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source