Results 101 to 110 of about 1,232,205 (304)
The Usual Suspects 2019: of Chips, Droplets, Synthesis, and Artificial Cells
Micromachines, 2019 Synthetic biology aims to understand fundamental biological processes in more detail than possible for actual living cells. Synthetic biology can combat decomposition and build-up of artificial experimental models under precisely controlled and defined ...
Christoph Eilenberger +5 more
doaj +1 more source
Sulphur systems biology—making sense of omics data
Journal of Experimental Botany, 2019 Systems biology approaches have been applied over the last two decades to study plant sulphur metabolism. These ‘sulphur-omics’ approaches have been developed in parallel with the advancing field of systems biology, which is characterized by permanent ...
Mutsumi Watanabe, R. Hoefgen
semanticscholar +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
BioPreDyn-bench: a suite of benchmark problems for dynamic modelling in systems biology
BMC Systems Biology, 2015 BackgroundDynamic modelling is one of the cornerstones of systems biology. Many research efforts are currently being invested in the development and exploitation of large-scale kinetic models.
A. F. Villaverde +12 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
, 2017 In this paper, we use Kansa method for solving the system of differential equations in the area of biology. One of the challenges in Kansa method is picking out an optimum value for Shape parameter in Radial Basis Function to achieve the best result of ...
Fallah, Mohammad Kazem +2 more
core
Use of Neurospora crassa as fungus model for systems biology of Moniliophthora perniciosa hyphae proteins: case study of polygalacturonases : S01P13 [PDF]
, 2013 Moniliophthora perniciosa, the fungus responsible for the witches' broom disease, brought serious problems to cacao (Theobroma cacao L.) cultivation in the infected areas such as in Southern Bahia, Brazil.
Carvalho, H.A.S. +2 more
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Experiment Selection for the Discrimination of Semi-Quantitative Models of Dynamical Systems [PDF]
, 2003 Modeling an experimental system often results in a number of alternative models that are all justified by the available experimental data. In order to discriminate between these models, additional experiments are needed.
Bernard, Olivier +3 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source