Results 61 to 70 of about 1,962,077 (344)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Knowledge Retention in Botswana’s Tourism and Hospitality Industry: Challenges and Prospects [PDF]

African Journal of Hospitality, Tourism and Leisure
This paper presents the findings of a study carried out to identify the challenges and prospects to retaining knowledge in Botswana’s tourism and hospitality industry. The study adopted a questionnaire survey approach for data collection.
Nametsegang MOTSHEGWA, Baoleki OSHAMO
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Explicit and implicit knowledge with regard to the age of learners

ExELL (Explorations in English Language and Linguistics), 2013
The present study set out to examine learners’ explicit and implicit foreign language knowledge with regard to their age. Therefore, two groups of learners from Zenica and Zavidovići (Bosnia and Herze-govina) presented the pool of informants in this ...
Vildana Dubravac
doaj  

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

The representation of explicit motor sequence knowledge [PDF]

Memory & Cognition, 2007
Much research has investigated the representation of implicitly learned motor sequences: Do subjects learn sequences of stimuli, responses, response locations, or some combination? Most of the work on this subject indicates that when sequences are learned implicitly, it is in terms of response locations. The present work investigated the representation
Robert, Knee, Sean, Thomason, James, Ashe, Daniel T, Willingham   +3 more
openaire   +2 more sources

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Implicit Knowledge, Explicit Knowledge, and Achievement in Second Language (L2) Spanish

Canadian Journal of Applied Linguistics, 2012
Implicit and explicit knowledge of the second language (L2) are two central constructs in the field of second language acquisition (SLA). In recent years, there has been a renewed interest in obtaining valid and reliable measures of L2 learners’ implicit
Xavier Gutiérrez
doaj  

Children's suggestibility in relation to their understanding about sources of knowledge [PDF]

, 2003
In the experiments reported here, children chose either to maintain their initial belief about an object's identity or to accept the experimenter's contradicting suggestion.
Foley M. A., Gopnik A., O'Neill D. K., Perner J., Pillow B. H., Robinson E. J., Robinson E. J., Robinson E. J., Ruffman T., Thierry K. L., Tulving E., Welch-Ross M.   +11 more
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source