Results 51 to 60 of about 4,738,289 (324)

Managing knowledge-related barriers to technological innovation through exploitative and explorative organisational strategies

open access: yes, 2019
This study uses data from a sample of 31,948 European innovating firms to examine the impact that knowledge-related barriers to technological innovation have on the link between the level of such innovation and firm performance, and, to investigate the ...
Torugsa, Nuttaneeya, O'Donohue, Wayne
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Does Innovation Lead to Firm Growth? : Explorative versus Exploitative Innovations

open access: yes, 2016
In this paper, we examine the relationship between innovation and firm growth. Weimplement a classification of innovations based on whether they are explorative orexploitative, taking advantage of a unique Swedish dataset for the period 1997 to 2012.The ...
Braunerhjelm, Pontus, Ding, Ding
core   +2 more sources

Research on the impact of data factor marketization on organizational resilience of resource-based enterprises: a moderated mediation model

open access: yesFrontiers in Communication
IntroductionThis study examines the impact of data element marketization on the organizational resilience of resource-based firms. Drawing on dynamic capability theory and ambidextrous innovation theory, it analyzes the chain mediation effect of ...
Fengzheng Wang   +3 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

The interplay of open innovation and strategic innovation: Unpacking the role of organizational learning ability and absorptive capacity

open access: yesInternational Journal of Engineering Business Management, 2022
We explore the open innovation research model in order to remove barriers in service organizations, where lack of knowledge is the main barrier to innovation.
Saima Mirza, Asif Mahmood, Hassan Waqar
doaj   +1 more source

The Role of Knowledge-Oriented Leadership in Fostering Innovation Capabilities: The Mediating Role of Data Analytics Maturity

open access: yesIEEE Access, 2023
The ability to continuously innovate has been widely realized as crucial for organizations to survive and be sustainable. One of the keys to successful innovation in a turbulent environment is leadership from top management and executives in ...
Destina Ratna Asih Khodijah Kadarsah   +2 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Now or never: Organizational forgetting as a determinant of knowledge sharing and cross-boundary innovation

open access: yesFrontiers in Psychology, 2022
This study constructs a theoretical model to test and prove that organizational forgetting influences cross-boundary innovation and testifies to the moderating role of Institutionalized organizational mission in the said relationship.
Xiaoyu Qu, Adnan Khan, Sajjad Ali
doaj   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Home - About - Disclaimer - Privacy