Results 61 to 70 of about 4,738,289 (324)

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Open Innovation Technologies and Exploitative and Explorative Learning

, 2012
Many organisations are embracing the open innovation approach. However, becoming open to ideas coming from outside requires a revision of their innovation processes in order to integrate external and internal ideas effectively. The aim of this chapter is
Mats Edenius, Edenius, Mats, Yakhlef, Ali,, Ali Yakhlef   +3 more
core   +1 more source

Effect of empowerment: how and when do high-involvement work practices influence elder employees’ innovative performance?

Frontiers in Psychology
IntroductionIn today’s fast-paced business environment, innovation from elder employees is increasingly vital to organizations. High-involvement work practices that emphasize engagement and empowerment have a significant impact on the innovation ...
Daokui Jiang, Yiting Zhang, Honghong Zhu, Xiaoyu Wang   +3 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Technology Licensing Agreements from an Organizational Learning Perspective

Asia Marketing Journal, 2013
New product innovation is a process of embodying new knowledge in a product and technology licensing is getting popular as a means to innovations and introduction of new product to the market in today`s competitive global market environment.
Jong Kuk Lee, Sang Young Song
doaj   +1 more source

The Effects of Workplace Belongingness on Exploratory Innovation: The Mediating Role of Exploitative Innovation

İşletme Araştırmaları Dergisi, 2020
Purpose – The study aims to explore the mediating role of exploitative innovation by revealing the effects of workplace belongingness and their effects on exploratory innovation in the IT industry.
F. Özsungur
semanticscholar   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Ambidexterity within a multinational context: how organisations can leverage explorative and exploitative reverse innovation

R&D Management
Organisational ambidexterity allows firms to maintain a competitive advantage. In today's globally competitive environment, characterised by dispersed knowledge and diversified markets, ambidexterity assumes an even more important connotation from a ...
Linus Roth, Simone Corsi, M. Hughes
semanticscholar   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The impact of managerial autonomy and founding-team marketing capabilities on the relationship between ambidexterity and innovation performance

Journal of Open Innovation: Technology, Market and Complexity
Despite extensive research on the impact of ambidexterity strategy on firm performance, little is known about how team and individual factors affect innovation performance in new-venture businesses. In response to the call for research on the topic, this
Sabaa Sayed, Mumin Dayan
doaj   +1 more source