Results 61 to 70 of about 56,888 (300)

From Strategic Congruence to Modeling and Simulation Ambidextrous Innovation: Evidence from Maritime Logistics

Systems
In highly dynamic and information-intensive logistics environments, understanding how firms achieve modeling and simulation ambidextrous innovation (MSAI) through strategic alignment is crucial.
Xinchen Wang, Mingjie Fang, Jia Shen
doaj   +1 more source

The Influences of Strategic Information Systems on the Relationship between Innovation and Organizational Performance

BBR: Brazilian Business Review, 2018
This study aims to identify the influences of strategic information systems (SIS) on the relationship of innovation (exploration/exploitation), ambidexterity and organizational performance (OP).
Adilson Carlos Yoshikuni, José Eduardo R. Favaretto, Alberto Luiz Albertin, Fernando de Souza Meirelles   +3 more
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

The Influence of Ambidextrous Knowledge Search on Technological Innovation: The Mediating Role of Knowledge Base

SAGE Open, 2023
As an effective means of acquiring knowledge resources, knowledge search is an important driving force for enterprises to obtain competitive advantages.
Hui Gao, Suming Wu
doaj   +1 more source

Ambidexterity as practice : individual ambidexterity through paradoxical practices [PDF]

, 2020
Following the turn to practice in organization theory and the emerging interest in the microfoundations of ambidexterity, understanding the role of individuals in realizing ambidexterity approaches becomes crucial.
Heracleous, Loizos Th., Papachroni, Angeliki   +1 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

Technological activities and their impact on the financial performance of the firm: Exploitation and exploration within and between firms. [PDF]

This article analyzes the financial performance consequences of technology strategies categorized along two dimensions: (1) explorative versus exploitative and (2) solitary versus collaborative.
Belderbos, Rene, Faems, Dries, Leten, Bart, Van Looy, Bart   +3 more
core   +3 more sources

The Renal Activity Index for Lupus Identifies Active Renal Disease and Treatment Response in Adult Patients With Systemic Lupus Erythematosus and Lupus Nephritis

Arthritis Care &Research, EarlyView.
Objective We evaluated the ability of the Renal Activity Index for Lupus (RAIL) to discriminate active lupus nephritis (LN) in adult patients with active systemic lupus erythematosus (SLE) and differentiate LN treatment response. Methods Urine samples from adults with biopsy‐proven active class III and IV LN from TULIP‐LN (active LN group ...
Hermine I. Brunner, Ellen M. Cody, Prasad Devarajan, Bin Huang, Chen Chen, Dominic Sinibaldi, Madhu Ramaswamy, Jacob Knagenhjelm, Frederick Jones, Philip Z. Brohawn, Raj Tummala, Catharina Lindholm, Wendy I. White   +12 more
wiley   +1 more source

Introducing conflict as the microfoundation of organizational ambidexterity [PDF]

, 2017
This article contributes to our understanding of organizational ambidexterity by introducing conflict as its microfoundation. Existing research distinguishes between three approaches to how organizations can be ambidextrous, that is, engage in both ...
Fortwengel, Johann, Keller, Arne, Martin, Alexander   +2 more
core   +2 more sources