Results 181 to 190 of about 15,762 (228)

Host-Directed Antiviral Strategies Against Influenza Viruses: Host Targets, Multi-Omics Approaches and AI-Assisted Discovery. [PDF]

Vet Sci
Hui X, Ding S, Gao S, Xu S, Zhao T, Tian X, Wang H.   +6 more
europepmc   +1 more source

Analysis of exportins expression unveils their prognostic significance in colon adenocarcinoma: insights from public databases. [PDF]

Discov Oncol
Kalia P, Nair RR, Yadav SS.
europepmc   +1 more source

Bruton's tyrosine kinase inhibitors in diffuse large B-cell lymphoma therapy: critical considerations and future innovations. [PDF]

J Transl Med
Lu C, Chen Q, Shen Y, Chen M, Xie Y, Wang C, Yu L.   +6 more
europepmc   +1 more source

Investigation of dynamic regulation of TFEB nuclear shuttling by microfluidics and quantitative modelling. [PDF]

Commun Biol
Ruolo I, Napolitano S, Postiglione L, Napolitano G, Ballabio A, di Bernardo D.   +5 more
europepmc   +1 more source

Selinexor plus tislelizumab in patients with relapsed/refractory natural killer/T-cell lymphoma after failure of PD-1 blockade: the phase 1b TOUCH trial. [PDF]

Oncologist
Liu C, Li D, Gao Y, Zhang W, Guo Z, Zhao J, Huang H, Tao R.   +7 more
europepmc   +1 more source

The Hidden Layer of MicroRNA Regulation in Gynecologic Cancers: IsomiRs, Arm Switching, and RNA Epitranscriptomic Modifications. [PDF]

Int J Mol Sci
Pérez-Navarro Y, López-Camarillo C, Flores-García LC, Alvarez-Sánchez ME, Campoy Ramírez A, Salinas-Vera YM.   +5 more
europepmc   +1 more source

Therapeutic Targeting of Exportin-1 in Childhood Cancer [PDF]

Cancers, 2021
Overexpression of Exportin-1 (XPO1), a key regulator of nuclear-to-cytoplasmic transport, is associated with inferior patient outcomes across a range of adult malignancies.
Daniel Weiser, Thomas B Alexander, Adam L Green   +2 more
exaly   +4 more sources

Exportin 4: a mediator of a novel nuclear export pathway in higher eukaryotes [PDF]

EMBO Journal, 2000
Transport receptors of the importin beta superfamily account for many of the nuclear import and export events in eukaryotic cells. They mediate translocation through nuclear pore complexes, shuttle between nucleus and cytoplasm and co-operate with the ...
Dirk Görlich, Ulrike Kutay, F R Bischoff   +2 more
exaly   +2 more sources

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Importins and exportins as therapeutic targets in cancer

Pharmacology & Therapeutics, 2016
The nuclear transport proteins, importins and exportins (karyopherin-β proteins), may play an important role in cancer by transporting key mediators of oncogenesis across the nuclear membrane in cancer cells. During nucleocytoplasmic transport of tumor suppressor proteins and cell cycle regulators during the processing of these proteins, aberrant ...
Amit, Mahipal, Mokenge, Malafa
openaire   +2 more sources