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Cancer-associated exportin-6 upregulation inhibits the transcriptionally repressive and anticancer effects of nuclear profilin-1 [PDF]
Aberrant expression of nuclear transporters and deregulated subcellular localization of their cargo proteins are emerging as drivers and therapeutic targets of cancer.
Cuige Zhu, Jason M. Held, Eugene M Oltz
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Journal of Virology, 2023
Flaviviruses have a cytoplasmic replication cycle, but recent evidence indicates that nuclear elements play a role in their viral replication. Viral proteins, such as NS5 and C, are imported into the nucleus, and blocking their import prevents replication.
Luis Adrián De Jesús-González +8 more
openaire +2 more sources
Flaviviruses have a cytoplasmic replication cycle, but recent evidence indicates that nuclear elements play a role in their viral replication. Viral proteins, such as NS5 and C, are imported into the nucleus, and blocking their import prevents replication.
Luis Adrián De Jesús-González +8 more
openaire +2 more sources
Key role of exportin 6 in exosome-mediated viral transmission from insect vectors to plants
Proceedings of the National Academy of Sciences of the United States of America, 2022Feng Cui, Qiong Li
exaly
CD47 interactions with exportin-1 limit the targeting of m7G-modified RNAs to extracellular vesicles
Journal of Cell Communication and Signaling, 2021Joshua Zimmerberg +2 more
exaly
The role of exportin‐t in selective nuclear export of mature tRNAs
EMBO Journal, 1998Pascale Romby +2 more
exaly
Leptomycin B alters the subcellular distribution of CRM1 (Exportin 1)
Biochemical and Biophysical Research Communications, 2017David A Dean
exaly
Re-evaluation of the roles of DROSHA, Exportin 5, and DICER in microRNA biogenesis
Proceedings of the National Academy of Sciences of the United States of America, 2016Young-Kook Kim +2 more
exaly

